SERPINA7 ELISA Kit

Produktnummer ABIN5510681

Dieses Human SERPINA7 ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Human SERPINA7 in zu quantifizieren.

Kurzübersicht für SERPINA7 ELISA Kit (ABIN5510681)

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Bindungsspezifität: AA 21-415

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails SERPINA7 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Serpin A7

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: A21-A415

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Expressed by the liver and secreted in plasma.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Andere Bezeichnung: SERPINA7

Hintergrund:

Protein Function: Major thyroid hormone transport protein in serum.

Background: Thyroxine-binding globulin (TBG), also known as SERPINA7, is the major thyroid hormone transport protein in serum. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. Using DNA blot hybridization, it is detected that there is a single-copy TBG gene located on the long arm of the X chromosome.

Synonyms: Thyroxine-binding globulin,Serpin A7,T4-binding globulin,SERPINA7,TBG,

Full Gene Name: Thyroxine-binding globulin

Cellular Localisation: Secreted.

UniProt: P05543

Pathways: Hormone Transport