WFDC2 ELISA Kit

Produktnummer ABIN5510648

Dieses Human WFDC2 ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Human WFDC2 zu quantifizieren. Dieses ELISA Kit wurde in 1 Publikation zitiert.

Kurzübersicht für WFDC2 ELISA Kit (ABIN5510648)

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Bindungsspezifität: AA 31-124

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails WFDC2 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human HE4

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: E.coli
Immunogen sequence: E31-F124

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. .

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Referenzen für WFDC2 ELISA Kit (ABIN5510648)

Dong, Liu, Li: "Value of HE4 Combined with Cancer Antigen 125 in the Diagnosis of Endometrial Cancer." in: Pakistan journal of medical sciences, Vol. 33, Issue 4, pp. 1013-1017, (2017) (PubMed).

Details zu WFDC2

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Andere Bezeichnung: WFDC2

Hintergrund:

Protein Function: Broad range protease inhibitor. .

Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4), is a protein that in humans is encoded by the WFDC2 gene. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

Synonyms: WAP four-disulfide core domain protein 2,Epididymal secretory protein E4,Major epididymis-specific protein E4,Putative protease inhibitor WAP5,WFDC2,HE4, WAP5,

Full Gene Name: WAP four-disulfide core domain protein 2

Cellular Localisation: Secreted.

UniProt: Q14508