Hemopexin ELISA Kit

Produktnummer ABIN5510645

Dieses Human Hemopexin ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Human Hemopexin zu quantifizieren.

Kurzübersicht für Hemopexin ELISA Kit (ABIN5510645)

Target: Hemopexin (HPX)

Bindungsspezifität: AA 24-462

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails Hemopexin ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Hemopexin

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: T24-H462

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Expressed by the liver and secreted in plasma.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu Hemopexin

Target: Hemopexin (HPX)

Andere Bezeichnung: HPX

Hintergrund:

Protein Function: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

Background: Hemopexin (or haemopexin, HPX), also known as beta-1B-glycoprotein, is a protein that in humans is encoded by the HPX gene and belongs to hemopexin family of proteins. Hemopexin binds heme with the highest affinity of any known protein. Its function is scavenging the heme released or lost by the turnover of heme proteins such as hemoglobin and thus protects the body from the oxidative damage that free heme can cause. In addition, hemopexin releases its bound ligand for internalisation upon interacting with a specific receptor situated on the surface of liver cells. This function of hemopexin is to preserve the body's iron.

Synonyms: Hemopexin,Beta-1B-glycoprotein,HPX,

Full Gene Name: Hemopexin

Cellular Localisation: Secreted.

UniProt: P02790

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response