PROCR ELISA Kit

Produktnummer ABIN5510637

Maus PROCR ELISA-Kit Colorimetric-Assay zur Quantifizierung von Maus PROCR.

Kurzübersicht für PROCR ELISA Kit (ABIN5510637)

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Bindungsspezifität: AA 18-214

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails PROCR ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated Mouse EPCR

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: L18-S214

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu PROCR

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Andere Bezeichnung: Procr

Hintergrund:

Protein Function: Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex, plays a role in the protein C pathway controlling blood coagulation.

Background: Endothelial protein C receptor (EPCR), also known as CCCA or PROCR, is a protein that in humans is encoded by the PROCR gene. PRPCR gene is mapped to 20q11.2 by radiation hybrid analysis and FISH. The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.

Synonyms: Endothelial protein C receptor,Activated protein C receptor,APC receptor,Centrocyclin,Centrosomal protein CCD41,Endothelial cell protein C receptor,CD201,Procr,Epcr,

Full Gene Name: Endothelial protein C receptor

Cellular Localisation: Membrane, Single-pass type I membrane protein.

UniProt: Q64695