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TIMP3 ELISA Kit

This anti-TIMP3 antibody (ABIN5510571) is a antibody detecting TIMP3 in ELISA. Suitable for Pig.
Produktnummer ABIN5510571

Quick Overview for TIMP3 ELISA Kit (ABIN5510571)

Target

Alle TIMP3 ELISA Kits anzeigen
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Bindungsspezifität

AA 24-211

Reaktivität

  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Schwein

Nachweismethode

Colorimetric

Methodentyp

Sandwich ELISA

Applikation

ELISA
  • Verwendungszweck

    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Pig porcine TIMP-3

    Marke

    PicoKine™

    Analytische Methode

    Quantitative

    Spezifität

    Expression system for standard: NSO
    Immunogen sequence: C24-P211

    Kreuzreaktivität (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Produktmerkmale

    Sequence similarities: Belongs to the protease inhibitor I35 (TIMP) family.

  • Plattentyp

    Pre-coated

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

    Haltbarkeit

    12 months
  • Target Alle TIMP3 ELISA Kits anzeigen

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    Andere Bezeichnung

    TIMP3

    Hintergrund

    Protein Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

    Background: The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).

    Synonyms: Metalloproteinase inhibitor 3,Protein MIG-5,Tissue inhibitor of metalloproteinases 3,TIMP-3,TIMP3,

    Full Gene Name: Metalloproteinase inhibitor 3

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.

    UniProt

    P35625
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