IGF2 ELISA Kit

Produktnummer ABIN5510551

Dieses Colorimetric ELISA-Kit wurde entwickelt für die quantitative Messung von Hamster IGF2.

Kurzübersicht für IGF2 ELISA Kit (ABIN5510551)

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Bindungsspezifität: AA 25-91

Reaktivität: Hamster

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails IGF2 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Chinese hamster IGF-2

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: E.coli
Immunogen sequence: A25-E91

Kreuzreaktivität (Details): There is no detectable cross-reactivity with IGF-1.

Produktmerkmale:

Sequence similarities: Belongs to the insulin family.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Andere Bezeichnung: Igf2

Hintergrund:

Protein Function: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.

Background: Insulin-like growth factor II is also known as somatomedin A. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is paternally expressed in the fetus and placenta. IGF-II is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the father is active and the allele inherited from the mother is inactive in most normal tissues. IGF-II appears to be induced by placental lactogen during prenatal development. It is a mediator of prolactin-induced alveologenesis, prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland.

Synonyms: Insulin-like growth factor II,IGF-II,Multiplication-stimulating activity,MSA,Multiplication-stimulating polypeptide,Insulin-like growth factor II,Preptin,Igf2,Igf-2,

Full Gene Name: Insulin-like growth factor II

Cellular Localisation: Secreted.

UniProt: P01346

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation