Rheumatoid Factor ELISA Kit

Produktnummer ABIN5068389

Maus Rheumatoid Factor ELISA-Kit Colorimetric-Assay zur Quantifizierung von Maus Rheumatoid Factor in Serum

Kurzübersicht für Rheumatoid Factor ELISA Kit (ABIN5068389)

Target: Rheumatoid Factor (RF)

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Proben: Serum

Produktdetails Rheumatoid Factor ELISA Kit

Produktmerkmale: Rheumatoid Factor (RF), Mouse, ELISA Kit

Bestandteile:

• Microwell Strips, 1x96 wells
• Negative Control, 1x1ml
• Positive Control, 1x1ml
• Sample Diluent, 10X, 1x10ml
• IgG (HRP), 100X GtxMo, 1x200ul
• Wash Buffer, 100X, 1x10ml
• TMB Substrate, 1x12ml
• Stop Solution. 1x12ml

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Informationen zur Lagerung: 4°C

Details zu Rheumatoid Factor

Target: Rheumatoid Factor (RF)

Hintergrund: Rheumatoid Factors (RFs) were described as Immunoglobulins (IgGs) in rheumatoid arthritis as detected by agglutination of rabbit IgG coated erythrocytes. It was later demonstrated that RFs were IgM molecules reactive with the Fc-portion of the IgG from various species. In addition to the IgM RF, subsequent studies have identified RFs of other IgG subtypes (IgG, IgA, and IgE) in sera of patients with rheumatoid arthritis, and certain other chronic diseases. Most commercial assays measure predominantly IgM RFs. It has been observed that measurement of IgG RF may be a better indicator of rheumatoid arthritis than IgM RF. IgA RF and IgE RF have been implicated in articular disease process in rheumatoid arthritis and rheumatoid vasculitis, respectively. RFs, produced by cells within the joint space, are found in joint fluids as well. RF titer, particularly IgG RF correlate with the intensity of synovitis.