NAMPT ELISA Kit

Produktnummer ABIN2745470

Human NAMPT ELISA-Kit Colorimetric-Assay zur Quantifizierung von Human NAMPT.

Kurzübersicht für NAMPT ELISA Kit (ABIN2745470)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 0.125-8 ng/mL

Applikation: ELISA

Proben: Serum

Produktdetails NAMPT ELISA Kit

Untere Nachweisgrenze: 0.125 ng/mL

Analytische Methode: Quantitative

Spezifität: Detects human Nampt.

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Weakly cross-reacts (<15 %) with mouse Nampt and rat Nampt. Does not cross-react with human adiponectin, human resistin, human vaspin or human RBP4. Has been shown to specifically detect the physiologically relevant Nampt dimer in human serum samples.

Sensitivität: 30 pg/mL

Produktmerkmale: Nampt (Visfatin/PBEF) (human) ELISA Kit (Twin Plex)

Anwendungsinformationen

Applikationshinweise: Note: Does not work with plasma samples.

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

Details zu NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Andere Bezeichnung: Nampt

Hintergrund: Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. It has been shown that Nampt expression is increased in different diseases, like diabetes, obesity, fetal growth retardation, sepsis, inflammatory bowel disease, Crohn's disease and rheumatoid arthritis. Furthermore, Nampt might be a marker of pre-eclampsia and of endothelial health.

UniProt: P43490