PRO-ANP ELISA Kit

Produktnummer ABIN2648514

Dieses Chemical PRO-ANP ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Chemical PRO-ANP zu quantifizieren.

Kurzübersicht für PRO-ANP ELISA Kit (ABIN2648514)

Target: PRO-ANP (Pro-Atrial Natriuretic Peptide (PRO-ANP))

Bindungsspezifität: N-Term

Reaktivität: Chemical

Nachweismethode: Colorimetric

Applikation: ELISA

Proben: Plasma, Urine, Serum, Cell Culture Supernatant

Produktdetails PRO-ANP ELISA Kit

Sensitivität: 0.05 nmol/L

Produktmerkmale: Atrial natriuretic peptide is synthesized in atrial myocytes and is stored in secretory granules as a 126 amino acid prohormone. The most important stimulus for the release of the hormone into circulation is stretch of the myocyte fibres. On release the prohormone is split into equimolar amounts of the highly biologically active proANP (99-126), also known as a-ANP, and the N-terminal part proANP (1-98). a-ANP is rapidly cleared from the circulation with a half-life of 3-4 minutes. proANP (1-98) has a much longer half-life (60-120 min) which leads to significantly higher concentrations in blood compared to a-ANP. Thus, circulating levels of proANP (1-98) are less sensitive to the pulsatile secretion of ANP and may better reflect chronic levels of ANP secretion than the rapidly fluctuating levels of a-ANP. proANP is discussed as valuable marker for e.g. sepsis (Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients. Hoffmann U. et al., Clin. Lab. 2005,51 (7-8):373-9), or risk stratification in heart failure (Neurohormonal risk stratification for sudden death and death owing to progressive heart failure in chronic heart failure. Berger R. et al, European Journal of Clinical Investigation, 2005, 35 (1), 24-31)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Probenmenge: 10 μL

Testdauer: 3.5 h

Plattentyp: Pre-coated

Protokoll: proANP (1-98) ELISA Assay KIT(enzyme-linked immunoassay kit) is intended for the quantitative determination of human, mouse, or rat proANP(1-98) in EDTA PLASMA, HEPARIN PLASMA, serum, URINE or CELL CULTURE SUPERNATANTS. proANP (1-98) ELISA Assay KIT is manufactured by Biomedica Gruppe (www.bmgrp.com) and is for research use only, not to be used in diagnostic procedures.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Details zu PRO-ANP

Target: PRO-ANP (Pro-Atrial Natriuretic Peptide (PRO-ANP))

Andere Bezeichnung: NT-ProANP