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TIMP3 ELISA Kit

Human TIMP3 ELISA-Kit Colorimetric-Assay zur Quantifizierung von Human TIMP3.
Produktnummer ABIN2042683

Kurzübersicht für TIMP3 ELISA Kit (ABIN2042683)

Target

Alle TIMP3 ELISA Kits anzeigen
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reaktivität

  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Nachweismethode

Colorimetric

Methodentyp

Sandwich ELISA

Detektionsbereich

6-10000 pg/mL

Applikation

ELISA
  • Untere Nachweisgrenze

    6 pg/mL

    Kreuzreaktivität (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivität

    < 2 pg/mL

    Bestandteile

    96-well plate pre-coated with anti-TIMP-3, Human
    Lyophilized recombinant TIMP-3, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plattentyp

    Pre-coated

    Protokoll

    Sandwich ELISA quantitative detection kit for Human TIMP-3 in cell culture supernates, serum, plasma (heparin, EDTA) and saliva.The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    4 °C/-20 °C
  • Target Alle TIMP3 ELISA Kits anzeigen

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    Andere Bezeichnung

    TIMP-3

    Gen-ID

    7078

    UniProt

    P35625
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