TIMP3 ELISA Kit
Kurzübersicht für TIMP3 ELISA Kit (ABIN2042683)
Target
Alle TIMP3 ELISA Kits anzeigenReaktivität
Nachweismethode
Methodentyp
Detektionsbereich
Applikation
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Untere Nachweisgrenze
- 6 pg/mL
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Kreuzreaktivität (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensitivität
- < 2 pg/mL
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Bestandteile
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96-well plate pre-coated with anti-TIMP-3, Human
Lyophilized recombinant TIMP-3, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plattentyp
- Pre-coated
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Protokoll
- Sandwich ELISA quantitative detection kit for Human TIMP-3 in cell culture supernates, serum, plasma (heparin, EDTA) and saliva.The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C/-20 °C
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- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
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Andere Bezeichnung
- TIMP-3
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Gen-ID
- 7078
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UniProt
- P35625
Target Alle TIMP3 ELISA Kits anzeigen
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