Granulin ELISA Kit

Produktnummer ABIN2042639

Produktdetails Granulin ELISA Kit

Target: Granulin (GRN)

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Detektionsbereich: 1.6-100 ng/mL

Untere Nachweisgrenze: 1.6 ng/mL

Applikation: ELISA

Marke: BioAssay™

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivität: < 50 pg/mL

Bestandteile: 96-well plate pre-coated with anti-Progranulin, Human
Lyophilized recombinant Progranulin, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Anwendungsinformationen

Plattentyp: Pre-coated

Protokoll: Sandwich ELISA quantitative detection kit for Human Progranulin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Granulin, also known as Proepithelin (PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88kD precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6kD peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu Granulin

Target: Granulin (GRN)

Andere Bezeichnung: Progranulin (GRN Produkte)

Synonyme: GRN ELISA Kit, grn ELISA Kit, wu:fb11g12 ELISA Kit, wu:fj18f05 ELISA Kit, MGC53354 ELISA Kit, DKFZp459H066 ELISA Kit, CLN11 ELISA Kit, GEP ELISA Kit, GP88 ELISA Kit, PCDGF ELISA Kit, PEPI ELISA Kit, PGRN ELISA Kit, epithelin ELISA Kit, acrogranin ELISA Kit, granulin precursor ELISA Kit, granulin a ELISA Kit, Granulins ELISA Kit, granulin L homeolog ELISA Kit, granulin ELISA Kit, GRN ELISA Kit, grna ELISA Kit, grn ELISA Kit, grn.L ELISA Kit, granulin ELISA Kit, ORF1 granulin ELISA Kit, Grn ELISA Kit

Substanzklasse: Viral Protein

Gen-ID: 2896

UniProt: P28799