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Granulin ELISA Kit

Dieses Colorimetric ELISA-Kit wurde entwickelt für die quantitative Messung von Human Granulin.
Produktnummer ABIN2042639
1.121,25 €
Zzgl. Versandkosten 20,00 € und MwSt
96 tests
Lieferung nach: Deutschland
Lieferung in 20 bis 26 Werktagen

Kurzübersicht für Granulin ELISA Kit (ABIN2042639)

Target

Alle Granulin (GRN) ELISA Kits anzeigen
Granulin (GRN)

Reaktivität

  • 10
  • 10
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Nachweismethode

Colorimetric

Methodentyp

Sandwich ELISA

Detektionsbereich

1.6-100 ng/mL

Applikation

ELISA
  • Untere Nachweisgrenze

    1.6 ng/mL

    Kreuzreaktivität (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivität

    < 50 pg/mL

    Bestandteile

    96-well plate pre-coated with anti-Progranulin, Human
    Lyophilized recombinant Progranulin, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plattentyp

    Pre-coated

    Protokoll

    Sandwich ELISA quantitative detection kit for Human Progranulin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Granulin, also known as Proepithelin (PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88kD precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6kD peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    4 °C/-20 °C
  • Target Alle Granulin (GRN) ELISA Kits anzeigen

    Granulin (GRN)

    Andere Bezeichnung

    Progranulin

    Substanzklasse

    Viral Protein

    Gen-ID

    2896

    UniProt

    P28799
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