IL-33 ELISA Kit

Produktnummer ABIN2042550

Dieses Human IL-33 ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Human IL-33 zu quantifizieren.

Kurzübersicht für IL-33 ELISA Kit (ABIN2042550)

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Competition ELISA

Detektionsbereich: 15.6-1000 pg/mL

Applikation: ELISA

Produktdetails IL-33 ELISA Kit

Untere Nachweisgrenze: 15.6 pg/mL

Marke: BioAssay™

Kreuzreaktivität (Details): No detectable crossreactivity with other relevant proteins

Sensitivität: < 10 pg/mL

Bestandteile: A: Microtiter Strip, 1x96 wells
B: IL-33 Standard, 2x10 ng
C: Anti-human IL-33 (Biotin), 130 µL

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C/-20 °C

Details zu IL-33

Target: IL-33 (IL33) (Interleukin 33 (IL33))

Andere Bezeichnung: IL-33

Hintergrund: Interleukin 33 (IL-33) is a cytokine belonging to the IL-1 superfamily. The IL33 gene maps to chromosome 9p24.1 by using of genomic database analysis. Recombinant mature human IL33 bound to ST2. The induction of type 2 cytokines by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of IL-33. IL33, an alarmin released from necrotic cells, is necessary for potent CD8 + T cell (CTL) responses to replicating, prototypic RNA, and DNA viruses in mice. IL33 prevented the downregulation of CXCR2 and inhibition of chemotaxis induced by activation of TLR4, and found that IL33 reverses the TLR4-induced reduction of CXCR2 expression via the inhibition of expression of GRK2.

Pathways: Production of Molecular Mediator of Immune Response