PF4 ELISA Kit
Kurzübersicht für PF4 ELISA Kit (ABIN2042428)
Target
Alle PF4 ELISA Kits anzeigenReaktivität
Nachweismethode
Methodentyp
Detektionsbereich
Applikation
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Untere Nachweisgrenze
- 15.6 pg/mL
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Kreuzreaktivität (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensitivität
- < 1 pg/mL
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Bestandteile
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96-well plate pre-coated with anti-CXCL4/PF4, Mouse
Lyophilized recombinant CXCL4/PF4, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plattentyp
- Pre-coated
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Protokoll
- Sandwich ELISA quantitative detection kit for Mouse CXCL4/PF4 in cell culture supernates, serum and plasma (heparin, EDTA).Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). The PF4 gene was localized on map to 4q12-q13. Chemokines play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C/-20 °C
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- PF4 (Platelet Factor 4 (PF4))
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Andere Bezeichnung
- CXCL4/PF4
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Gen-ID
- 56744
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UniProt
- Q9Z126
Target Alle PF4 ELISA Kits anzeigen
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