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PF4 ELISA Kit

Maus PF4 ELISA-Kit Colorimetric-Assay zur Quantifizierung von Maus PF4.
Produktnummer ABIN2042428

Kurzübersicht für PF4 ELISA Kit (ABIN2042428)

Target

Alle PF4 ELISA Kits anzeigen
PF4 (Platelet Factor 4 (PF4))

Reaktivität

  • 9
  • 8
  • 8
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Maus

Nachweismethode

Colorimetric

Methodentyp

Sandwich ELISA

Detektionsbereich

15.6-1000 pg/mL

Applikation

ELISA
  • Untere Nachweisgrenze

    15.6 pg/mL

    Kreuzreaktivität (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivität

    < 1 pg/mL

    Bestandteile

    96-well plate pre-coated with anti-CXCL4/PF4, Mouse
    Lyophilized recombinant CXCL4/PF4, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plattentyp

    Pre-coated

    Protokoll

    Sandwich ELISA quantitative detection kit for Mouse CXCL4/PF4 in cell culture supernates, serum and plasma (heparin, EDTA).Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). The PF4 gene was localized on map to 4q12-q13. Chemokines play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    4 °C/-20 °C
  • Target Alle PF4 ELISA Kits anzeigen

    PF4 (Platelet Factor 4 (PF4))

    Andere Bezeichnung

    CXCL4/PF4

    Gen-ID

    56744

    UniProt

    Q9Z126
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