SensoLyte® 490 MMP-2 Assay Kit

Produktnummer ABIN1882518

Kurzübersicht für SensoLyte® 490 MMP-2 Assay Kit (ABIN1882518)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Nachweismethode: Fluorometric

Applikation: Fluorescence Resonance Energy Transfer Microscopy (FRET)

Produktdetails

Marke: SensoLyte®

Produktmerkmale: The SensoLyte® 490 MMP-2 Assay Kit is a complete assay system designed to continuously analyze MMP activities or to screen MMP-2 inhibitors by using a fluorogenic MMP-2 substrate.

Anwendungsinformationen

Kommentare:

FRET-based Assay Kit

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Protect Components A and B from light.

Lagerung: -20 °C

Informationen zur Lagerung: Store all components at -20 °C. Components D and E can be stored at 4 °C for convenience.

Referenzen

Mei, Li, Chu, Yiu, Lo: "The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases." in: Dental materials : official publication of the Academy of Dental Materials, Vol. 28, Issue 8, pp. 903-8, (2012) (PubMed).

Djouad, Rackwitz, Song, Janjanin, Tuan: "ERK1/2 activation induced by inflammatory cytokines compromises effective host tissue integration of engineered cartilage." in: Tissue engineering. Part A, Vol. 15, Issue 10, pp. 2825-35, (2009) (PubMed).

Antigendetails

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP-2

Hintergrund: Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion is well known. MMP-2 (gelatinase A) is proposed as a potential therapeutic target.