anti-SRC (SRC) Antikörper

Bezeichnung:: anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) Antikörper (SRC)

Auf www.antikoerper-online.de finden Sie aktuell 468 V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Antikörper von 31 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SRC Proteine (20) und SRC Kits (15) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 529 SRC Produkte verfügbar.

Synonyme:: ASV, AW259666, c-Src, C-src1, CG7524, D-src, D-Src64B, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, p60-Src, PP60C-SCR, pp60c-src, SDR, src, SRC1, src64, SRC 64B, src64b

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	SRC	20779	P05480
	SRC	6714	P12931
	SRC	83805
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Mouse (Murine) SRC Antikörper:

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Am meisten referenzierte anti-SRC Antikörper

Human Polyclonal SRC Primary Antibody für IHC - ABIN967081 : David-Dufilho, Millanvoye-Van Brussel, Topal, Walch, Brunet, Rendu: Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II. in The Journal of biological chemistry 2005 (PubMed)
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Human Polyclonal SRC Primary Antibody für FACS, IF - ABIN1881833 : Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. in Cell stem cell 2010 (PubMed)
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Human Polyclonal SRC Primary Antibody für WB - ABIN1881832 : Pradhan, Alrehani, Patel, Khatlani, Vijayan: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen. in The Journal of biological chemistry 2010 (PubMed)
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Human SRC Primary Antibody für IHC - ABIN967080 : Parker, Mardon, Lebo, Varmus, Bishop: Isolation of duplicated human c-src genes located on chromosomes 1 and 20. in Molecular and cellular biology 1985 (PubMed)
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Human Polyclonal SRC Primary Antibody für IHC - ABIN967082 : Pyper, Bolen: Identification of a novel neuronal C-SRC exon expressed in human brain. in Molecular and cellular biology 1990 (PubMed)
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Human Monoclonal SRC Primary Antibody für ELISA, WB - ABIN1724696 : Li, Aurandt, Jürgensen, Jürgense, Rao, Guan: FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5. in Journal of cell science 2005 (PubMed)
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Chicken Monoclonal SRC Primary Antibody für ICS - ABIN1177179 : Alvarez, Kantarjian, Cortes: The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors. in Cancer 2006 (PubMed)
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Chicken Monoclonal SRC Primary Antibody für ICS - ABIN1177181 : Arias-Salgado, Lizano, Sarkar, Brugge, Ginsberg, Shattil: Src kinase activation by direct interaction with the integrin beta cytoplasmic domain. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
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Chicken Monoclonal SRC Primary Antibody für ICS - ABIN1177180 : Frame: Newest findings on the oldest oncogene; how activated src does it. in Journal of cell science 2004 (PubMed)
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Human Monoclonal SRC Primary Antibody für ELISA, WB - ABIN967078 : Zheng, Yano, Matsumori, Nakataki, Muguruma, Yoshizumi, Sone et al.: SRC tyrosine kinase inhibitor, m475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma ... in Clinical & experimental metastasis 2005 (PubMed)
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Weitere Antikörper gegen SRC Interaktionspartner

Mouse (Murine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

Src kinase (zeige CSK Antikörper) activation by nitric oxide promotes resistance to anoikis in tumor cell lines.
RANKL (zeige TNFSF11 Antikörper) and Src has an unrecognized role in osteocyte survival.
These interactions are required for SRC-induced activation of VAV (zeige VAV1 Antikörper) and the subsequent engagement of a JIP1 (zeige MAPK8IP1 Antikörper)-tethered JNK (zeige MAPK8 Antikörper) signaling module.
Elevated retinoic acid-inducible gene 1 (zeige RARRES3 Antikörper) (RIG-I (zeige DDX58 Antikörper)) modulated the interaction of activated proto-oncogene c-Src (Src) and STAT3 (zeige STAT3 Antikörper) by competitive binding to STAT3 (zeige STAT3 Antikörper).
Cbl, Cbl-b, and Cbl-c have a role in protecting mammary epithelial cellsfrom proteotoxic stress-induced cell death by promoting turnover of active c-Src
unlike c-fos-/- mice, c-src-/- mice demonstrated activated, mature osteoblasts, and parallel layers of cement lines in the superficial bone matrix, indicating the new bones were piled up to older bone.
TM, especially TME45, maintains vascular integrity, at least in part, via Src signaling.
We conclude that pp60(Src) can directly inhibit DDAH (zeige DDAH2 Antikörper) II and this is involved in the increased ADMA levels that enhance eNOS (zeige NOS3 Antikörper) uncoupling during the development of acute lung injury (ALI).
Ambra1 (zeige AMBRA1 Antikörper) binds to both FAK (zeige PTK2 Antikörper) and Src in cancer cells. When FAK (zeige PTK2 Antikörper) is present, Ambra1 (zeige AMBRA1 Antikörper) is recruited to focal adhesions, promoting FAK (zeige PTK2 Antikörper)-regulated cancer cell direction-sensing and invasion. However, when Ambra1 (zeige AMBRA1 Antikörper) cannot bind to FAK (zeige PTK2 Antikörper), abnormally high levels of phospho-Src and phospho-FAK (zeige PTK2 Antikörper) accumulate at focal adhesions, positively regulating adhesion and invasive migration.
Thus we propose that Cx43 (zeige GJA1 Antikörper) might enhance the activation of Nrf2 (zeige NFE2L2 Antikörper)/ARE pathway by means of inhibiting c-Src activity to hinder the nuclear export of Nrf2 (zeige NFE2L2 Antikörper), and then reduce expression of FN, ICAM-1 (zeige ICAM1 Antikörper) and TGF-b1, ultimately attenuating renal fibrosis in diabetes.

Fruit Fly (Drosophila melanogaster) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo
that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction
Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.
a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.
Data show that the actin-Capping Protein (zeige TMOD4 Antikörper) (CP) alphabeta heterodimer, which regulates actin (zeige ACTB Antikörper) filament (F-actin (zeige ACTB Antikörper)) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK (zeige MAPK8 Antikörper) activation.
Dumbfounded/Neph1 (zeige NEPH1 Antikörper), a key diaphragm constituent, is a target of the Src kinase (zeige CSK Antikörper) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (zeige NEPH1 Antikörper) tyrosine phosphorylation.
Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B in the developing embryonic central nervous system.
E4orf4 has a role in inducing PP2A (zeige PPP2R2B Antikörper)- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster
Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.
Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (zeige ACTB Antikörper) formation and Jun kinase (zeige MAPK9 Antikörper) activation in plasmatocytes.

Human V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

Src kinase (zeige CSK Antikörper) activation by nitric oxide promotes resistance to anoikis in tumor cell lines.
Src and Aurora-A (zeige AURKA Antikörper) interact upon Golgi ribbon fragmentation; Src phosphorylates Aurora-A (zeige AURKA Antikörper) at tyrosine 148 and this specific phosphorylation is required for Aurora-A (zeige AURKA Antikörper) localization at the centrosomes.
Study demonstrated that c-Src contributed to hypoxic microenvironment-rendered paclitaxel resistance in human epithelial ovarian cancer cells by G2/M phase arrest deterioration, and through c-Src suppression, FV-429 was capable of reversing the resistance by blocking c-Src/Stat3 (zeige STAT3 Antikörper)/HIF-1alpha (zeige HIF1A Antikörper) pathway.
Data demonstrated that the Src/Fn14 (zeige TNFRSF12A Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) axis plays a critical role in NSCLC metastasis.
Results suggest that Src promotes EGF (zeige EGF Antikörper)-stimulated EMT (zeige ITK Antikörper) and migration by upregulation of ZEB1 (zeige ZEB1 Antikörper) and ZEB2 (zeige ZEB2 Antikörper) through AKT (zeige AKT1 Antikörper) signaling pathway in gastric cancer cells.
Combined targeting of AKT (zeige AKT1 Antikörper) and SRC resulted in a synergistic efficacy against human pancreatic cancer growth and metastasis.
important roles for c-Src tyrosine kinase (zeige CSK Antikörper) in phosphorylation and activation of SLC11A1 (zeige SLC11A1 Antikörper) in macrophages
Our data suggest that targeting Src signaling may be an effective approach to the treatment of ALK-non-small cell lung cancer (NSCLC) with acquired resistance to ALK inhibitors.
Src kinase (zeige CSK Antikörper) in chemo-naive human primary osteosarcoma cells is differentially activated.
This study demonstrates that simultaneous inhibition of c-Met and Src signaling in MD-MSCs triggers apoptosis and reveals vulnerable pathways that could be exploited to develop NF2 (zeige NF2 Antikörper) therapies.

Cow (Bovine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

RhoA (zeige RHOA Antikörper) and membrane fluidity mediates the spatially polarized Src/FAK (zeige PTK2 Antikörper) activation in response to shear stress.
AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.
The Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.
src has a role in activation of 5'-AMP (zeige TMPRSS5 Antikörper)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells
results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network
These results suggest that TGF-beta1 (zeige TGFB1 Antikörper)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK (zeige PTK2 Antikörper)/Src-dependent and -independent pathways.

Pig (Porcine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Interaktionspartner

The findings are consistent with previous studies that indicate a link between Na,K-ATPase (zeige ATP1A1 Antikörper) activity and SFK signaling.
Src kinase (zeige CSK Antikörper) mediates hypoxia-induced caspase-1 (zeige CASP1 Antikörper) activation in the cerebral cortex of newborn piglets
Expression of mutant alpha1 Na/K-ATPase (zeige ATP1A1 Antikörper) defective in conformational transition attenuates Src-mediated signal transduction
20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

SRC Antigen-Profil

Beschreibung des Gens

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SRC

SRC proto-oncogene, non-receptor tyrosine kinase (SRC) Antikörper
uncharacterized LOC5574802 (LOC5574802) Antikörper
proto-oncogene tyrosine-protein kinase src (CpipJ_CPIJ010659) Antikörper
Rous sarcoma oncogene (Src) Antikörper
Src oncogene at 64B (Src64B) Antikörper
SRC proto-oncogene, non-receptor tyrosine kinase (Src) Antikörper

ASV Antikörper
AW259666 Antikörper
c-Src Antikörper
C-src1 Antikörper
CG7524 Antikörper
D-src Antikörper
D-Src64B Antikörper
Dmel\CG7524 Antikörper
DmHD-358 Antikörper
Dm SRC1 Antikörper
dsrc Antikörper
Dsrc64 Antikörper
Dsrc64B Antikörper
HD-358 Antikörper
MRE5 Antikörper
p60-Src Antikörper
PP60C-SCR Antikörper
pp60c-src Antikörper
SDR Antikörper
src Antikörper
SRC1 Antikörper
src64 Antikörper
SRC 64B Antikörper
src64b Antikörper

Bezeichner auf Proteinebene für SRC

, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , proto-oncogene tyrosine-protein kinase SRC proto-oncogene tyrosine-protein kinase src neuronal proto-oncogene tyrosine-protein kinase Src p60-Src proto-oncogene c-Src CG7524-PB CG7524-PC CG7524-PD CG7524-PE CG7524-PF CG7524-PG CG7524-PH CG7524-PI CG7524-PJ Src proto oncogene sequence Src64B-PB Src64B-PC Src64B-PD Src64B-PE Src64B-PF Src64B-PG Src64B-PH Src64B-PI Src64B-PJ mRNA-like ncRNA in embryogenesis 5 proto-oncogene tyrosine-protein kinase Src protooncogene SRC, Rous sarcoma tyrosine kinase pp60c-src tyrosine-protein kinase SRC-1 Rous sarcoma oncogene c-Src pp60c-src tyrosine protein kinase c-src tyrosine protein kinase pp60-c-src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog src oncogene v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog non-tyrosine protein kinase

GENE ID	SPEZIES
458229	Pan troglodytes
5574802	Aedes aegypti
6043642	Culex quinquefasciatus
20779	Mus musculus
48973	Drosophila melanogaster
6714	Homo sapiens
83805	Rattus norvegicus
485864	Canis lupus familiaris
535742	Bos taurus
100154503	Sus scrofa
396442	Gallus gallus

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