anti-IL12RB2 (IL12RB2) Antikörper

Bezeichnung:: anti-Interleukin 12 Receptor, beta 2 Antikörper (IL12RB2)

Auf www.antikoerper-online.de finden Sie aktuell 100 Interleukin 12 Receptor, beta 2 (IL12RB2) Antikörper von 20 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IL12RB2 Proteine (21) und IL12RB2 Kits (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 137 IL12RB2 Produkte verfügbar.

Synonyme:: A930027I18Rik, Ifnm, IL-12RB2, IL12RB2

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	IL12RB2	16162	P97378
	IL12RB2	171334
	IL12RB2	3595	Q99665
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-IL12RB2 (IL12RB2) Antikörper

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anti-Mouse (Murine) IL12RB2 Antikörper:

anti-Rat (Rattus) IL12RB2 Antikörper:

anti-Human IL12RB2 Antikörper:

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Verknüpfte Pathways mit anti-IL12RB2 Antikörper

JAK-STAT Signalweg

Weitere Produktkategorien zu IL12RB2 Antikörper

Am meisten referenzierte anti-IL12RB2 Antikörper

Mouse (Murine) Monoclonal IL12RB2 Primary Antibody für FACS - ABIN2689735 : Chakir, Camilucci, Filion, Webb: Differentiation of murine NK cells into distinct subsets based on variable expression of the IL-12R beta 2 subunit. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
Show all 10 Pubmed References
Human Monoclonal IL12RB2 Primary Antibody für FACS - ABIN4897167 : Nguyen, Frye, Zbesko, Stepanovic, Hayes, Urzua, Serrano, Beach, Doyle: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue. in Acta neuropathologica communications 2016 (PubMed)
Show all 2 Pubmed References
Human Monoclonal IL12RB2 Primary Antibody für FACS - ABIN4897173 : Cunningham, Cardwell, Guan, Teixeiro, Daniels: POSH Regulates CD4+ T Cell Differentiation and Survival. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
Show all 2 Pubmed References
Human Polyclonal IL12RB2 Primary Antibody für IF (p), IHC (p) - ABIN747878 : Filková, Vernerová, Hulejová, Prajzlerová, Veigl, Pavelka, Vencovský, Šenolt: Pro-inflammatory effects of interleukin-35 in rheumatoid arthritis. in Cytokine 2015 (PubMed)

Weitere Antikörper gegen IL12RB2 Interaktionspartner

Mouse (Murine) Interleukin 12 Receptor, beta 2 (IL12RB2) Interaktionspartner

These results provide a new pathway of Th1 (zeige HAND1 Antikörper) response regulation where IL-12 (zeige IL12A Antikörper) secreted by dendritic cellss is consumed by a sub-population of IL-12Rbeta2-expressing Treg cells.
in neonatal mice, IL-12 (zeige IL12A Antikörper) uses IL-12Rbeta2 to counter IL-13Ralpha1 expression in addition to promoting Th1 (zeige HAND1 Antikörper) differentiation
Data indicate that delayed induction of the IL-12Rbeta2 receptor component after STAT1 (zeige STAT1 Antikörper) activation helped ensure that Treg cells do not readily complete STAT4 (zeige STAT4 Antikörper)-dependent Th1 (zeige HAND1 Antikörper) cell development and lose their ability to suppress effector T cell proliferation.
Signaling through the IL-35 receptor required the transcription factors STAT1 (zeige STAT1 Antikörper) and STAT4 (zeige STAT4 Antikörper).
Data show that T(H)1 differentiation was impaired in Il2 (zeige IL2 Antikörper)(-/-) T cells but was restored by IL-12Rbeta2 expression.
gamma rays cause a decrease in IFN-gamma (zeige IFNG Antikörper), IL-12p70, IL-12 (zeige IL12A Antikörper) receptor beta2, and STAT4 (zeige STAT4 Antikörper) and an increase in IL-4 (zeige IL4 Antikörper) in natural killer cells
Freshly isolated ex vivo T helper (Th)17 cells display restricted expression from Il12rb2 due to the presence of repressive chromatin remodeling.
T-bet mediates STAT1 (zeige STAT1 Antikörper)-dependent processes of T(H)1 development, including the induction of IL-12Rbeta2.
NO activates soluble guanylyl cyclase, leading to the up-regulation of cGMP, which selectively induces the expression of IL-12 (zeige IL12A Antikörper) receptor beta2.
Contrary to the expectation that the absence of IL-12RB2 would protect from experimental autoimmune encephalitis, IL-12RB2-deficient mice develop earlier and more severe disease, with extensive demyelination and central nervous system inflammation.

Human Interleukin 12 Receptor, beta 2 (IL12RB2) Interaktionspartner

The Cox (zeige COX8A Antikörper) proportional hazard models revealed that IL12Rb2 and p38MAPK (zeige MAPK14 Antikörper) predicted a long OS. To the best of our knowledge, the present study is the first to reveal a close association between IL12Rb2 and p38MAPK (zeige MAPK14 Antikörper), and their possible function in nonsmall cell lung cancer progression
Tumor cell differentiation is associated with TILs' expression of IL-12Rbeta2, and an IL-12Rbeta2(+) TIL (zeige TLR1 Antikörper) ratio >/=35%) indicates favorable prognosis in LC
inhibition of the H3K27 demethylase (zeige MBD2 Antikörper) JMJD3 (zeige Kdm6b Antikörper) in naive CD4 (zeige CD4 Antikörper) T cells demonstrates how critically important molecules required for T cell differentiation, such as JAK2 (zeige JAK2 Antikörper) and IL12RB2, are regulated by H3K27me3.
this study identified susceptibility single nucleotide polymorphisms in IL12RB2 with Behcet's disease in Han Chinese
In ankylosing spondylitis, conditional analysis identified rs11209032 as the probable causal single-nucleotide polymorphism within a 1.14 kb putative enhancer between IL23R (zeige IL23R Antikörper) and IL12RB2. The rs11209032 single-nucleotide polymorphism downstream of IL23R (zeige IL23R Antikörper) forms part of an enhancer, allelic variation of which may influence Th1 (zeige TH1L Antikörper)-cell numbers.
The results of this case-control study suggest that IL-12A (zeige IL12A Antikörper), IL-12B (zeige IL12B Antikörper), IL12RB1 (zeige IL12RB1 Antikörper), IL12RB2 and IL23R (zeige IL23R Antikörper) make no genetic contribution to the susceptibility of Takayasu arteritis in Chinese populations
study confirmed the relationship of IL12RB2 polymorphisms with primary biliary cholangitis (PBC (zeige DLAT Antikörper)) susceptibility; provided evidence that IL12RB2 polymorphisms are associated with liver cirrhosis and an increased concentration of disease-specific anti-mitochondrial antibodies in sera of PBC (zeige DLAT Antikörper) patients
this study shows that single nucleotide polymorphisms of the IL23R-IL12RB2 region are associated with Behcet's disease in a Northern Chinese Han population
IL12RB2 polymorphisms correlate with risk of lung adenocarcinoma.
The effects of rs3762315 and rs3762316 single nucleotide polymorphisms in 5' flanking region on IL12RB2 transcription

Cow (Bovine) Interleukin 12 Receptor, beta 2 (IL12RB2) Interaktionspartner

Four SNPs in IFNGR2 (zeige IFNGR2 Antikörper), IL12RB1 (zeige IL12RB1 Antikörper), IL12RB2, and IL23R (zeige IL23R Antikörper) were found to be associated with the MAP infection status of the resource population.

IL12RB2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

Alternative names and synonyms associated with IL12RB2

interleukin 12 receptor subunit beta 2 (IL12RB2) Antikörper
interleukin 12 receptor, beta 2 (Il12rb2) Antikörper
interleukin 12 receptor subunit beta 2 (Il12rb2) Antikörper

A930027I18Rik Antikörper
Ifnm Antikörper
IL-12RB2 Antikörper
IL12RB2 Antikörper

Bezeichner auf Proteinebene für IL12RB2

interleukin 12 receptor, beta 2 , interleukin 12 receptor beta-2 , interleukin-12 receptor subunit beta-2 , interleukin-12 receptor subunit beta-2-like , IL-12 receptor subunit beta-2 , IL-12R subunit beta-2 , IL-12R-beta-2 , interferon response to microorganisms , interleukin-12 receptor beta-2 chain , IL-12RB2 , interleukin-12 receptor beta 2 , IL-12 receptor beta-2

GENE ID	SPEZIES
469348	Pan troglodytes
489550	Canis lupus familiaris
700677	Macaca mulatta
100393796	Callithrix jacchus
100456779	Pongo abelii
100582797	Nomascus leucogenys
16162	Mus musculus
171334	Rattus norvegicus
3595	Homo sapiens
424705	Gallus gallus
397178	Sus scrofa
282452	Bos taurus

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