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Mouse (Murine) IL-3 Protein expressed in Escherichia coli (E. coli) - ABIN1305116
Urdal, Mochizuki, Conlon, March, Remerowski, Eisenman, Ramthun, Gillis: Lymphokine purification by reversed-phase high-performance liquid chromatography. in Journal of chromatography 1984
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Human IL-3 Protein expressed in Escherichia coli (E. coli) - ABIN1305115
Frendl: Interleukin 3: from colony-stimulating factor to pluripotent immunoregulatory cytokine. in International journal of immunopharmacology 1992
Show all 3 Pubmed References
Human IL-3 Protein expressed in Escherichia coli (E. coli) - ABIN803865
Han, Kitamoto, Wang, Boisvert: Interleukin-10 overexpression in macrophages suppresses atherosclerosis in hyperlipidemic mice. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010
Human IL-3 Protein expressed in Escherichia coli (E. coli) - ABIN1112336
Vicker: F-actin assembly in Dictyostelium cell locomotion and shape oscillations propagates as a self-organized reaction-diffusion wave. in FEBS letters 2001
Human IL-3 Protein expressed in Escherichia coli (E. coli) - ABIN413516
Kinzfogl, Hangoc, Broxmeyer: Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. in Blood 2011
These impaired macrophage functions in leukemic mice were significantly corrected by IL-3 and GM-CSF (zeige CSF2 Proteine) treatment indicating the therapeutic benefit of these two cytokines in leukemia.
IL-3 signaling does not contribute to Jak2 (zeige JAK2 Proteine) V617F myeloproliferative neoplasm pathogenesis.
Thus, IL-3 plays an important role in the pathogenesis of SLE and the progression of lupus nephritis.
Cytoplasmic granule containing HERMES (zeige CD44 Proteine), NonO (zeige NONO Proteine), PSF, and G3BP1 (zeige G3BP1 Proteine) is a neuronal RNA-protein granule that is transported in neurites during retinal differentiation.
Stem cell factor (SCF (zeige KITLG Proteine)), but not interleukin-3 (IL-3), is a major effector of HSC (zeige FUT1 Proteine) maturation during embryonic day E9-E10.
study reports IL3 potentiates inflammation in sepsis; in model of abdominal sepsis, findings show innate response activator B cells produce IL3, which induces myelopoiesis of monocytes and neutrophils and fuels cytokine storm; IL3 deficiency protects against sepsis
these findings reveal a role for CSF-1 (zeige CSF1 Proteine) in mediating the IL-3 hematopoietic pathway through monopoiesis, which regulates expansion of CD11c (zeige ITGAX Proteine)+ macrophages.
Altered expression of CD30L (zeige TNFSF8 Proteine) and IL-3 may be potential biomarkers for hepatotoxicity induced by D. bulbifera.
This study is the first to link beta-catenin (zeige CTNNB1 Proteine) activation to IL-3 and suggests that targeting IL-3 signaling may be an effective approach for the inhibition of beta-catenin (zeige CTNNB1 Proteine) activity in some patients with AML (zeige RUNX1 Proteine).
IL-3 plays a critical role in suppressing protective immunity to P. berghei NK65 infection.
T-GM-CSF (zeige CSF2 Proteine) and -IL-3 significantly, and reciprocally, blunted receptor binding and myeloid progenitor cell proliferation activity of both FL-GM-CSF (zeige CSF2 Proteine) and -IL-3 in vitro and in vivo
Results show that IL-3 induces several signaling pathways associated with increased cell survival under oxidative stress. This activity correlates with previous fi ndings indicating glucose uptake stimulation by IL-3, which together contribute to an emerging picture of a broader mechanism promoting cell survival.
The IL-3/ GM-CSF (zeige CSF2 Proteine) effected on the myofibroblastic differentiation of human adipose derive stromal cells (hASCs) as well as it did on human dermal fibroblasts (HDFs).
Genetically engineered mesenchymal stromal cells produce IL-3 and TPO (zeige THPO Proteine) to further improve human scaffold-based xenograft models
IL-3 hardly down-regulates the alpha-chain (zeige FCGRT Proteine) of its receptor without depleting the common beta-chain (zeige CSF2RB Proteine), which enables extraordinarily sustained signaling events, predominantly the activation of Stat5 (zeige STAT5A Proteine).
genetic polymorphisms in the immune genes IL-3 rs181781 and CTLA4 (zeige CTLA4 Proteine) rs4553808 may influence the TAC (zeige IL2RA Proteine) dose-adjusted concentrations
Our results indicated that the IL-3 and IL-13 (zeige IL13 Proteine) polymorphisms were not associated with rheumatoid arthritis (RA). stratification analyses suggested that the IL-13 (zeige IL13 Proteine) rs1800925 CT and CT/CC genotypes increased the risk of RA in patients with erythrocyte sedimentation rate (ESR (zeige ESR1 Proteine)) <25.00. these findings suggest that the IL-13 (zeige IL13 Proteine) rs1800925 C/T polymorphism may be associated with increased risk of RA in ESR (zeige ESR1 Proteine)
results suggest that IL-3 and IL-12p40 could be considered as molecular predictors for recurrent wheezing due to RSV infection
results suggest that IL3 is an important genetic regulator for human brain volume variation and implied that IL3 might have experienced weak or modest positive selection in the evolutionary history of humans
Thymic stromal lymphopoietin (zeige TSLP Proteine) activation of basophils in patients with allergic asthma is IL-3 dependent
cytokine that functions as a multi-lineage haemopoietic growth regulator
, hematopoietic growth factor
, mast cell growth factor
, multipotential colony-stimulating factor
, P-cell stimulating factor
, mast-cell growth factor
, multilineage-colony-stimulating factor
, colony-stimulating factor, multiple
, Hematopoietic growth factor
, Mast cell growth factor
, Multipotential colony-stimulating factor