GM-CSF Proteine
(Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008].
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CSF2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CSF2
Spezies: Maus
Wirt: Human Cells
Recombinant
> 95 % as determined by SDS-PAGE
Active
CSF2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE
Active
CSF2
Spezies: Maus
Wirt: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
CSF2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CSF2
Spezies: Ratte
Wirt: Human Cells
Recombinant
> 95 % as determined by SDS-PAGE
1 image
CSF2
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
CSF2
Spezies: Human
Wirt: HEK-293 Cells
> 95 %
AcA, CC
Active
2 Abbildungen
CSF2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 98 % by SDS-PAGE
Active
CSF2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CSF2
Spezies: Ratte
Wirt: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
CSF2
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CSF2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
CSF2
Spezies: Human
Wirt: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
CSF2
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CSF2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, Ct
CSF2
Spezies: Human
Wirt: Yeast (Pichia pastoris)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Func
Active
CSF2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CSF2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Func
Active
CSF2
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
Aktuelle Publikationen für unsere GM-CSF Proteine
: "Linoleic acid inhibits in vitro function of human and murine dendritic cells, CD4+T cells and retinal pigment epithelial cells." in: Graefe's archive for clinical and experimental ophthalmology, (2020) (PubMed).: "Decreased expression of A20 is associated with ocular Behcet's disease (BD) but not with Vogt-Koyanagi-Harada (VKH) disease." in: The British journal of ophthalmology, Vol. 102, Issue 8, pp. 1167-1172, (2019) (PubMed).
: "Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells." in: Scientific reports, Vol. 7, Issue 1, pp. 8519, (2019) (PubMed).
: "Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model." in: Scientific reports, Vol. 7, pp. 43322, (2018) (PubMed).
: "Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease." in: Scientific reports, Vol. 7, Issue 1, pp. 1007, (2017) (PubMed).
: "GM-CSF-DFF40: a novel humanized immunotoxin induces apoptosis in acute myeloid leukemia cells." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 7, pp. 882-95, (2013) (PubMed).
: "Characterization of pathogenic human monoclonal autoantibodies against GM-CSF." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 19, pp. 7832-7, (2013) (PubMed).
: "Dectin-1/TLR2 and NOD2 agonists render dendritic cells susceptible to infection by X4-using HIV-1 and promote cis-infection of CD4(+) T cells." in: PLoS ONE, Vol. 8, Issue 7, pp. e67735, (2013) (PubMed).
: "Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy." in: The Journal of experimental medicine, Vol. 210, Issue 11, pp. 2223-37, (2013) (PubMed).
: "Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells." in: Blood, Vol. 118, Issue 3, pp. 565-75, (2011) (PubMed).
Aliase für GM-CSF Proteine
colony stimulating factor 2 (CSF2) Proteinecolony stimulating factor 2 (granulocyte-macrophage) (Csf2) Proteine
colony stimulating factor 2 (Csf2) Proteine
colony stimulating factor 2 (granulocyte-macrophage) (CSF2) Proteine
CSF Proteine
CSF2 Proteine
Csfgm Proteine
GM-CSF Proteine
Gm-CSf Proteine
Gm-csf Proteine
GMCSF Proteine
Gmcsf Proteine
MGI-IGM Proteine
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