Rekombinanter Human IgG2 Isotyp-Kontrolle
In vivo Grade
IsoC, in vivo
IgG2
Recombinant Antibody
unconjugated
Produktnummer ABIN7211742
-15% Promotion 2026
555,77 €
Sparen Sie 98,08 € (-15 %)
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach:
Deutschland
Lieferung in 7 bis 9 Werktagen
Kurzübersicht für Rekombinanter Human IgG2 Isotyp-Kontrolle (ABIN7211742)
Target
IgG2
Antikörpertyp
Recombinant Antibody
Applikation
Isotype Control (IsoC), In vivo Studies (in vivo)
Güteklasse
In vivo Grade
Isotyp
IgG2
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Reaktivität
- Human
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Wirt
- Human
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Expressionssystem
- Mammalian cells
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Verwendungszweck
- In Vivo Grade Recombinant Human IgG2 Fc Protein
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Produktmerkmale
- Human Fc (IgG2) is the tail region of an immunoglobulin G2 (IgG2) that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. The ~230 amino acid fragment generally exists as a dimer, although under reducing conditions, it exists as a monomer. It is the basis of prolonged pharmacokinetics of antibodies and is commonly used as a fusion to extend half-life of fusion proteins. IgG2 has a shorter hinge than IgG1, with 12 amino acid residues and four disulfide bridges at the Fab base. The hinge region of IgG2 also lacks a glycine residue, which along with its shortness almost completely prevents rotation and restricts lateral movement of the Fabs.
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by SDS-PAGE under reducing conditions
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Sterilität
- Sterile filtered
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Endotoxin-Niveau
- < 1 EU per 1 mg of the protein by the LAL method
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4
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Lagerung
- 4°C,-20 °C
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Informationen zur Lagerung
- 1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.
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Haltbarkeit
- 3 months
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- IgG2
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Substanzklasse
- Antibody
Target
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