HEK-293 Cells IgG1 Isotyp-Kontrolle

Details zu Produkt Nr. ABIN2181271, Anbieter: Anmelden zum Anzeigen
Isotyp
  • IgG1
  • Igh-4
  • VH7183
  • immunoglobulin heavy constant gamma 1 (G1m marker)
  • Ighg1
Reaktivität
Human
Wirt
HEK-293 Cells
245
83
22
9
3
3
2
1
1
1
1
Biologische Aktivität
Active
Applikation
Isotype Control (IsoC)
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Isotyp IgG1
Produktmerkmale This protein carries no "tag". The protein has a calculated MW of 26 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Reinheit >95 % as determined by SDS-PAGE.
Sterilität 0.22 μm filtered
Endotoxin-Niveau Less than 1.0 EU per μg by the LAL method.
Hintergrund Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Molekulargewicht 26 kDa
UniProt P01857
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C in lyophilized state after receipt. For long term storage, upon reconstitution rhIgG1 Fc should be aliquot and store at -20°C or -80°C.
Bilder des Herstellers
SDS-PAGE (SDS) image for HEK-293 Cells IgG1 isotype control (ABIN2181271) Human IgG1 Fc, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained...