anti-NCOA4 (NCOA4) Antikörper

Bezeichnung:: anti-Nuclear Receptor Coactivator 4 Antikörper (NCOA4)

Auf www.antikoerper-online.de finden Sie aktuell 86 Nuclear Receptor Coactivator 4 (NCOA4) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NCOA4 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 99 NCOA4 Produkte verfügbar.

Synonyme:: 1110034E15Rik, 4432406M01Rik, AI227008, ARA70, DKFZp459B2429, DKFZp469A035, DKFZp469A1925, ELE1, MGC84996, MGC138109, ncoa4, PTC3, Rfg, zgc:55307, zgc:77270

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	NCOA4	619385
	NCOA4	8031	Q13772
	NCOA4	27057
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Rat (Rattus) NCOA4 Antikörper:

anti-Human NCOA4 Antikörper:

anti-Mouse (Murine) NCOA4 Antikörper:

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Verknüpfte Pathways mit anti-NCOA4 Antikörper

Intracellular Steroid Hormone Receptor Signaling Pathway

Weitere Produktkategorien zu NCOA4 Antikörper

Am meisten referenzierte anti-NCOA4 Antikörper

Human Monoclonal NCOA4 Primary Antibody für IF, ELISA - ABIN521736 : Poola, Abraham, Marshalleck, Yue, Fu, Viswanath, Sharma, Hill, Dewitty, Bonney: Molecular constitution of breast but not other reproductive tissues is rich in growth promoting molecules: a possible link to highest incidence of tumor growths. in FEBS letters 2009 (PubMed)

Weitere Antikörper gegen NCOA4 Interaktionspartner

Xenopus laevis Nuclear Receptor Coactivator 4 (NCOA4) Interaktionspartner

NCOA4 acts as a regulator of DNA replication origins that helps prevent inappropriate DNA synthesis and replication stress.

Human Nuclear Receptor Coactivator 4 (NCOA4) Interaktionspartner

The H-ferritin could bind up to 24 NCOA4(383-522) fragments forming highly stable and insoluble complexes. The binding was partially inhibited only by Fe(II) among the various divalent metal ions analyzed. The iron-dependent, highly-specific formation of the remarkably stable H-ferritin-NCOA4 complex shown in this work may be important for the characterization of the mechanism of ferritinophagy.
the ATG5 (zeige ATG5 Antikörper)-ATG7 (zeige ATG7 Antikörper)-NCOA4 autophagic pathway has a role in ferroptosis
Ubiquitin-dependent NCOA4 turnover is promoted by excess iron and involves an iron-dependent interaction between NCOA4 and the HERC2 ubiquitin ligase.
Studies indicate nuclear receptor coactivator 4 (NcoA4) as a coactivator for a variety of nuclear receptors.
provide a new mechanism for selective autophagy of ferritin (zeige FTL Antikörper) and reveal a previously unappreciated role for autophagy and NCOA4 in the control of iron homeostasis in vivo
RET (zeige RET Antikörper)/PTC3 gene rearrangements are the most prevalent form of rearrangements in papillary thyroid carcinomas of Chennai population.
NCOA4 acts as a regulator of DNA replication origins that helps prevent inappropriate DNA synthesis and replication stress.
identification of NCOA4 as a selective cargo receptor for autophagic turnover of ferritin (zeige FTL Antikörper) (ferritinophagy), which is critical for iron homeostasis, and provides a resource for further dissection of autophagosomal cargo-receptor connectivity
mechanism dissection shows that KLK2 (zeige KLK2 Antikörper) may cooperate with the AR coregulator, ARA70, to enhance AR transactivation that may result in alteration of prostate cancer formation
Data indicate that the increase in prostate cancer (PC) risk associated with rs10993994:C>T is likely mediated by the variant's effect of MSMB (zeige MSMB Antikörper)-encoded protein PSP94 (zeige MSMB Antikörper) expression; however, this effect does not extend to NCOA4 in the data.

Mouse (Murine) Nuclear Receptor Coactivator 4 (NCOA4) Interaktionspartner

These studies demonstrate the importance of ferritin (zeige FTL Antikörper) for the vectorial transfer of imported iron to mitochondria in developing red cells and of PCBP1 (zeige PCBP1 Antikörper) and NCOA4 in mediating iron flux through ferritin (zeige FTL Antikörper).
NCOA4 prevents iron accumulation and ensures efficient erythropoiesis, playing a central role in balancing iron levels in vivo.
provide a new mechanism for selective autophagy of ferritin (zeige FTL Antikörper) and reveal a previously unappreciated role for autophagy and NCOA4 in the control of iron homeostasis in vivo
NCOA4 acts as a regulator of DNA replication origins that helps prevent inappropriate DNA synthesis and replication stress.
Results demonstrate ubiquitous NcoA4 expression throughout development and suggest that this coactivator may play a role in modulating nuclear receptor activity, particularly that of the aryl hydrocarbon receptor (zeige AHR Antikörper), during development.
Data suggest that myostatin (zeige MSTN Antikörper) decreases the activity of androgen receptors (AR) by down-regulating the expression of ARA70, a known stimulating co-factor of AR

NCOA4 Antigen-Profil

Beschreibung des Gens

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Alternative names and synonyms associated with NCOA4

nuclear receptor coactivator 4 (Ncoa4) Antikörper
nuclear receptor coactivator 4 (ncoa4) Antikörper
nuclear receptor coactivator 4 (NCOA4) Antikörper
nuclear receptor coactivator 4 S homeolog (ncoa4.S) Antikörper

1110034E15Rik Antikörper
4432406M01Rik Antikörper
AI227008 Antikörper
ARA70 Antikörper
DKFZp459B2429 Antikörper
DKFZp469A035 Antikörper
DKFZp469A1925 Antikörper
ELE1 Antikörper
MGC84996 Antikörper
MGC138109 Antikörper
ncoa4 Antikörper
PTC3 Antikörper
Rfg Antikörper
zgc:55307 Antikörper
zgc:77270 Antikörper

Bezeichner auf Proteinebene für NCOA4

nuclear receptor coactivator 4 , Nuclear receptor coactivator 4 , 70 kDa AR-activator , 70 kDa androgen receptor coactivator , NCoA-4 , RET-activating gene ELE1 , androgen receptor-associated protein of 70 kDa , ret fused

GENE ID	SPEZIES
619385	Rattus norvegicus
394104	Danio rerio
423615	Gallus gallus
450455	Pan troglodytes
525329	Bos taurus
734285	Xenopus laevis
100156184	Sus scrofa
100172727	Pongo abelii
100306816	Salmo salar
8031	Homo sapiens
27057	Mus musculus

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