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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
CG12031-PA , CG12031-PB , MED14-PA , MED14-PB , mediator complex subunit 14 , cofactor required for Sp1 transcriptional activation, subunit 2 , mediator of RNA polymerase II transcription subunit 14 , cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa , mediator of RNA polymerase II transcription subunit 14-like , ARC150 , CRSP complex subunit 2 , RGR1 homolog , activator-recruited cofactor 150 kDa component , cofactor required for Sp1 transcriptional activation, subunit 2 (150kD) , hRGR1 , human homolog of yeast RGR1 , thyroid hormone receptor-associated protein complex 170 kDa component , thyroid hormone receptor-associated protein complex component TRAP170 , transcriptional co-activator CRSP150 , vitamin D receptor-interacting protein complex component DRIP150 , vitamin D3 receptor-interacting protein complex 150 kDa component , cofactor required for Sp1 transcriptional activation subunit 2 (150 kDa) , hypothetical protein
GENE ID | SPEZIES |
---|---|
38073 | Drosophila melanogaster |
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418572 | Gallus gallus |
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529109 | Bos taurus |
699395 | Macaca mulatta |
100017367 | Monodelphis domestica |
100082286 | Ornithorhynchus anatinus |
100113592 | Nasonia vitripennis |
100379915 | Xenopus (Silurana) tropicalis |
100398339 | Callithrix jacchus |
100469732 | Ailuropoda melanoleuca |
100515423 | Sus scrofa |
100544637 | Meleagris gallopavo |
100561165 | Anolis carolinensis |
100583512 | Nomascus leucogenys |
9282 | Homo sapiens |
26896 | Mus musculus |
317343 | Rattus norvegicus |
101123354 | Ovis aries |
3637672 | Candida albicans SC5314 |