PTGES2 Proteine (PTGES2)

Bezeichnung:: Prostaglandin E Synthase 2 Proteine (PTGES2)

Auf www.antikoerper-online.de finden Sie aktuell 15 Prostaglandin E Synthase 2 (PTGES2) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PTGES2 Antikörper (70) und PTGES2 Kits (34) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 128 PTGES2 Produkte verfügbar.

Synonyme:: 0610038H10Rik, C9orf15, C79137, GBF-1, Gbf1, MPGES-2, Mpges2, Pges2, ptges2, zgc:56527

alle Proteine anzeigen	Gen	GeneID	UniProt
	PTGES2	80142	Q9H7Z7
	PTGES2	96979	Q8BWM0
Ratte PTGES2	PTGES2	311865
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Human Prostaglandin E Synthase 2 (PTGES2) Interaktionspartner

Four single nucleotide polymorphisms in two genes in the PGE2 family, PTGES2 and PTGER4 (zeige PTGER4 Proteine), were significantly associated with primary graft dysfunction after lung transplantation.
high immunoreactivity of mPGES-2 in pyramidal neurons of AD brains indicates that it might have a potential role in the functional replacement of cytosolic PGES (zeige PTGES Proteine) or inactive mPGES-1 (zeige PTGES Proteine) in later stages of Alzheimer disease
Up-regulation of prostaglandin E2 synthesis by interleukin-1beta in human orbital fibroblasts involves coordinate induction of prostaglandin-endoperoxide H synthase-2 and glutathione-dependent prostaglandin E2 synthase expression
role in regulating interferon-gamma (zeige IFNG Proteine)-dependent gene expression
110Cys is essential in the active site of membrane-associated prostaglandin E synthase-2
Transactivators GBF1 and CCAAT/enhancer-binding protein-beta (zeige CEBPB Proteine) physically interact to induce interferon-gamma (zeige IFNG Proteine)-regulated transcription; a 37-aa long peptide derived from the GBF1 protein can associate with C/EBP-beta (zeige CEBPB Proteine) in an IFN-inducible manner.
alphaTOS inhibits COX (zeige COX8A Proteine) activity, thereby inhibiting PGE2 production in human lung epithelial cells
study obtained evidence from two Caucasian study populations that the His298-allele of PTGES2 Arg298His confers to reduced risk of type 2 diabetes
Carbonyl reductase-1 (CBR1 (zeige CBR1 Proteine)), microsomal prostaglandin E synthase-1 (zeige PTGES Proteine) and 2 (mPGES-1 (zeige PTGES Proteine), mPGES-2), cytosolic prostaglandin E synthase (cPGES (zeige PTGES3 Proteine)), aldoketoreductase (AKR1C1 (zeige DDH Proteine)) and prostaglandin F synthase (AKR1C3 (zeige AKR1C3 Proteine)) were all expressed in hair follicles.
risk-reducing effects of the minor His allele of the prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism could be mediated partly by lowered body mass index (BMI)

Mouse (Murine) Prostaglandin E Synthase 2 (PTGES2) Interaktionspartner

mPGES-2 deletion enhanced streptozotocin (STZ)-induced liver toxicity possibly via GLUT2-mediated STZ uptake, independently of diabetes mellitus in mice.
increased expression of miR (zeige MLXIP Proteine)-146a in bone marrow-derived mesenchymal stem cells correlated with inhibition of prostaglandin E2 synthase-2 and inhibition of prostaglandin E2 release.
Transactivators GBF1 and CCAAT/enhancer-binding protein-beta (zeige CEBPB Proteine) physically interact to induce interferon-gamma (zeige IFNG Proteine)-regulated transcription; a 37-aa long peptide derived from the GBF1 protein can associate with C/EBP-beta (zeige CEBPB Proteine) in an IFN-inducible manner.
In the urogenital system, membrane-associated PGES-2 was highly expressed in the renal cortex, followed by the renal medulla and ovary, with lower levels in the ureter, bladder and uterus.
Study suggests that in hypertensive mice, there are (a) significant microanatomic variations in the pulmonary, renal, and cardiac distribution and cellular localization of mPGES-2 and no differences in expression between genders.
Analysis of the mPGES-2 deficient mouse lines does not substantiate the contention that mPGES-2 is a PGE (zeige LIPF Proteine)(2) synthase.
This article reviews the involvement of the PGE(2), Wnt, and BMP pathways in the development of gastric cancer.
PGE (zeige LIPF Proteine)(2) protects the pulmonary vasculature from remodeling during allergen-induced pulmonary inflammation

PTGES2 Protein Überblick

Protein Überblick

The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.

Alternative names and synonyms associated with PTGES2

prostaglandin E synthase 2 (PTGES2)
prostaglandin E synthase 2-like (ptgesl)
prostaglandin E synthase 2 (CpipJ_CPIJ003988)
prostaglandin E synthase 2 (CpipJ_CPIJ018524)
prostaglandin E synthase 2 (ptges2)
prostaglandin E synthase 2 (Ptges2)

0610038H10Rik Protein
C9orf15 Protein
C79137 Protein
GBF-1 Protein
Gbf1 Protein
MPGES-2 Protein
Mpges2 Protein
Pges2 Protein
ptges2 Protein
zgc:56527 Protein

Bezeichner auf Proteinebene für PTGES2

prostaglandin E synthase 2 , mPGES-2 , microsomal prostaglandin E synthase 2 , prostaglandin E synthase 2-like , GATE-binding factor 1 , gamma-interferon-activated transcriptional element-binding factor 1 , membrane-associated prostaglandin E synthase 2 , microsomal prostaglandin E synthase-2

GENE ID	SPEZIES
464763	Pan troglodytes
697949	Macaca mulatta
799964	Danio rerio
6035489	Culex quinquefasciatus
6052766	Culex quinquefasciatus
100038070	Xenopus (Silurana) tropicalis
100443538	Pongo abelii
100590065	Nomascus leucogenys
80142	Homo sapiens
96979	Mus musculus
311865	Rattus norvegicus
100725206	Cavia porcellus
100155133	Sus scrofa
493639	Bos taurus
609101	Canis lupus familiaris
417214	Gallus gallus
101109261	Ovis aries

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