Felodipine
Kurzübersicht für Felodipine (ABIN1027921)
Applikation
Chemical Name
-
-
Verwendungszweck
- L-type Ca channel blocker
-
Produktmerkmale
- L-type Ca channel blocker.
-
Reinheit
- >98 % (TLC), NMR (Conforms)
-
Formel
- C18H19Cl2NO4
-
Löslichkeit
- Soluble to 100 mM in ethanol and to 100 mM in DMSO
-
-
-
-
Kommentare
-
Source: Synthetic.
Appearance: Light Yellow Solid -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Solid
-
Vorsichtsmaßnahmen
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302
-
Handhabung
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302
-
Lagerung
- -20 °C
-
-
-
Hintergrund
- Felodipine is an L-type Ca2+ channel blocker. In isolated rat ventricular myocytes, using a whole-cell patch-clamp technique, it displays a Ki of 11 nM. It is a clinically useful antihypertensive agent which attenuates the hypertrophic effect of cyclosporine on transplanted hearts.
-
Molekulargewicht
- 384.25
-
CAS-Nummer
- 72509-76-3
-
-