Capsaicin
Kurzübersicht für Capsaicin (ABIN1027919)
Applikation
Chemical Name
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Verwendungszweck
- TRPV1 opener
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Produktmerkmale
- TRPV1opener.
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Reinheit
- >60 % (HPLC), NMR (conforms)
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Formel
- C18H27NO3
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Löslichkeit
- Soluble in DMSO (20 mg/mL) and ethanol (15 mg/mL)
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Kommentare
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Source: Synthetic.
Appearance: Off-White Solid -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Solid
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Vorsichtsmaßnahmen
- Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R25-37/38-41-42/43 Hazard Phrases: H301-H311-H315-H317-H318-H334-H335 Precautionary Phrases: P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
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Handhabung
- Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R25-37/38-41-42/43 Hazard Phrases: H301-H311-H315-H317-H318-H334-H335 Precautionary Phrases: P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
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Lagerung
- -20 °C
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Hintergrund
- Capsaicin is an agonist at the TRPV1 receptor, a ligand-gated non-selective cation channel. It exhibits neuroprotective effects in a model of transient global cerebral ischemia and induces release of substance P from afferent nociceptive specific neurons. Powerful excitant of peripheral sensory nerve endings, specifically unmyelinated afferent neurons (C-fibers). Reversibly inhibits aggregation of platelets.
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Molekulargewicht
- 305.41
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CAS-Nummer
- 404-86-4
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