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Astemizole

BR, Inh 68844-77-9 1-(4-Fluorobenzyl)-N-{1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl}-1H-benzimidazol-2-amine, Hismanal
Produktnummer ABIN1027879
253,93 €
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 7 bis 10 Werktagen

Kurzübersicht für Astemizole (ABIN1027879)

Applikation

Blocking Reagent (BR), Inhibition (Inh)

Chemical Name

1-(4-Fluorobenzyl)-N-{1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl}-1H-benzimidazol-2-amine, Hismanal
  • Verwendungszweck

    Herg channel blocker

    Produktmerkmale

    Herg channel blocker.

    Reinheit

    >98 %

    Formel

    C28H31FN4O

    Löslichkeit

    Soluble to 100 mM in DMSO and to 25 mM in ethanol
  • Kommentare

    Source: Synthetic.
    Appearance: White solid

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Solid

    Vorsichtsmaßnahmen

    Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62 - Possible risk of impaired fertility Hazard Phrases: H315-H319-H335 Precautionary Phrases: P261-P305 + P351 + P338

    Handhabung

    Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62 - Possible risk of impaired fertility Hazard Phrases: H315-H319-H335 Precautionary Phrases: P261-P305 + P351 + P338

    Lagerung

    -20 °C
  • Hintergrund

    Astemizole is a second generation antihistamine drug which has a long duration of action. It binds to histamine H1-receptor sites in the gastrointestinal tract, uterus, blood vessels and bronchial muscle. It does not cross the blood-brain barrier, and the binding is primarily in the peripheral nervous system. It is metabolized by CYP3A4.
    Synonyms: Hismanal

    Molekulargewicht

    458.57

    CAS-Nummer

    68844-77-9
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