Mifepristone (RU486)
Kurzübersicht für Mifepristone (RU486) (ABIN1027778)
Applikation
Chemical Name
-
-
Verwendungszweck
- Glucocorticoid antagonist
-
Produktmerkmale
- Glucocorticoid antagonist.
-
Reinheit
- >98 %
-
Formel
- C29H35NO2
-
Löslichkeit
- Soluble to 100 mM in DMSO, and to 50 mM in ethanol
-
-
-
-
Kommentare
-
Source: Synthetic.
Appearance: Yellow solid -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Solid
-
Vorsichtsmaßnahmen
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H360 Precautionary Phrases: P201-P308 + P313
-
Handhabung
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R60- May impair fertility R61- May cause harm to the unborn child Hazard Phrases: H360 Precautionary Phrases: P201-P308 + P313
-
Lagerung
- -20 °C
-
-
-
Hintergrund
- Mifepristone is a progesterone receptor antagonist used as an abortifacient. It is also an antiglucocorticoid and an antiandrogen. Its relative binding affinity at the progesterone receptor is twice that of progesterone, its affinity at the glucocorticoid receptor is 3x that of dexamethasone, and more than 10 times that of cortisol.
-
Molekulargewicht
- 429.6
-
CAS-Nummer
- 84371-65-3
-
-