INSIG1 Produkte
(Insulin Induced Gene 1 (INSIG1))
Kategorien
Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jun 2009].
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Ausgewählte INSIG1 Kategorien
INSIG1 Antikörper
High quality antibodies with extensive validation data.
Empfohlene INSIG1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7156348
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN652887
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6262599
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene INSIG1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6228955
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene INSIG1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3124684
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3109916
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7422967
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren INSIG1 Produkten
: "LncRNA as ceRNAs may be involved in lactation process." in: Oncotarget, Vol. 8, Issue 58, pp. 98014-98028, (2017) (PubMed).: "Analysis of the protein network of cholesterol homeostasis in different brain regions: an age and sex dependent perspective." in: Journal of cellular physiology, Vol. 228, Issue 7, pp. 1561-7, (2013) (PubMed).
: "Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system." in: Acta physiologica (Oxford, England), Vol. 206, Issue 1, pp. 62-71, (2012) (PubMed).
: "Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin." in: Biochimie, Vol. 93, Issue 7, pp. 1165-71, (2011) (PubMed).
: "Sex differences in hepatic regulation of cholesterol homeostasis." in: The Journal of endocrinology, Vol. 198, Issue 3, pp. 635-43, (2008) (PubMed).
: "Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression." in: Molecular pharmacology, Vol. 73, Issue 4, pp. 1282-9, (2008) (PubMed).
: "Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake." in: Cell metabolism, Vol. 3, Issue 1, pp. 15-24, (2006) (PubMed).
: "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." in: The Journal of clinical investigation, Vol. 115, Issue 9, pp. 2489-98, (2005) (PubMed).
Synonyme und alternative Namen zu INSIG1
insulin induced gene 1 (INSIG1), insulin induced gene 1 (insig1), insulin induced gene 1 L homeolog (insig1.L), insulin induced gene 1 (Insig1), 1810013C12Rik, cl-6, CL-6, cl6, CL6, fb55a03, fi35b10, Insig-1, INSIG-1, wu:fb55a03, wu:fi35b10, zgc:55439Bezeichner auf Proteinebene für INSIG1
- insulin induced gene 1
- INSIG-1
- insulin-induced gene 1 protein
- INSIG-1 membrane protein
- growth response protein (CL-6)
- immediate-early protein CL-6
- insulin-induced growth response protein CL-6
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