IL-37 Proteine
(Interleukin 37 (IL37))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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IL37
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % as determined by SDS-PAGE
Func
Active
1 image
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % (SDS-PAGE)
SDS
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % (SDS-PAGE)
SDS
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
IL37
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
IL37
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
IL37
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
IL37
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
IL37
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % as determined by SDS-PAGE.
WB
Aktuelle Publikationen für unsere IL-37 Proteine
: "Elevated plasma interleukin-37 playing an important role in acute coronary syndrome through suppression of ROCK activation." in: Oncotarget, Vol. 8, Issue 6, pp. 9686-9695, (2018) (PubMed).: "Interleukin-37 ameliorates myocardial ischaemia/reperfusion injury in mice." in: Clinical and experimental immunology, Vol. 176, Issue 3, pp. 438-51, (2014) (PubMed).
: "Interleukin-37 is elevated in subjects with atopic dermatitis." in: Journal of dermatological science, Vol. 69, Issue 2, pp. 173-5, (2013) (PubMed).
Aliase für IL-37 Proteine
interleukin 37 (IL37) ProteineFIL1 Proteine
FIL1(ZETA) Proteine
FIL1Z Proteine
IL-1F7 Proteine
IL-1H Proteine
IL-1H4 Proteine
IL-1RP1 Proteine
IL-37 Proteine
IL1F7 Proteine
IL1H4 Proteine
IL1RP1 Proteine
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