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IL-10 Proteine

(Interleukin 10 (IL10))
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011].

118 Treffer

IL10 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB
Produktnummer ABIN5608269
610,50 €
Zzgl. Versandkosten 20,00 € und MwSt
20 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen
 
IL10 Spezies: Maus Wirt: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB
Produktnummer ABIN5608270
551,38 €
Zzgl. Versandkosten 20,00 € und MwSt
20 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen
 
IL10 Spezies: Schwein Recombinant
Produktnummer ABIN1064698
4.199,64 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg (Weitere Mengeneinheiten)
Lieferung nach: Deutschland
Lieferung in 10 bis 12 Werktagen
 
IL10 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, Imm, ELISA
Produktnummer ABIN7894923
1.889,00 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, Imm, ELISA
Produktnummer ABIN7894925
1.889,00 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Human Wirt: Mammalian Cells Recombinant WB, SDS, Imm, ELISA
Produktnummer ABIN7894924
3.281,00 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Maus Wirt: Bacteria Recombinant
Produktnummer ABIN7820064
302,50 €
Zzgl. Versandkosten 20,00 €, Trockeneispauschale 20,00 € sowie MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 4 bis 5 Werktagen
 
IL10 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7934940
4.893,90 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7934941
3.892,90 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Human Wirt: Human Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7934942
3.892,90 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Macaca (Macaque) Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE.
Produktnummer ABIN7934943
2.767,60 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Macaca (Macaque) Wirt: Mammalian Cells Recombinant Greater than 85 % as determined by SDS-PAGE.
Produktnummer ABIN7934946
5.746,40 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Macaca (Macaque) Wirt: Baculovirus infected Insect Cells Recombinant Greater than 90 % as determined by SDS-PAGE.
Produktnummer ABIN7934944
3.036,00 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Macaca (Macaque) Wirt: Baculovirus infected Insect Cells Recombinant Greater than 85 % as determined by SDS-PAGE.
Produktnummer ABIN7934945
2.765,40 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >97 % as determined by SDS-PAGE and HPLC. Active
Produktnummer ABIN7937177
7.566,90 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS-PAGE and HPLC analyses. Active
Produktnummer ABIN7937178
354,20 €
Zzgl. Versandkosten 20,00 € und MwSt
10 μg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE and HPLC. Active
Produktnummer ABIN7937176
7.566,90 €
Zzgl. Versandkosten 20,00 € und MwSt
1 mg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
IL10 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 97 % by SDS-PAGE and HPLC analyses. Active
Produktnummer ABIN7937179
354,20 €
Zzgl. Versandkosten 20,00 € und MwSt
10 μg
Lieferung nach: Deutschland
Lieferung in 12 bis 17 Werktagen
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Biochemical Assay (BCA)
    • Functional Studies (Func)
    • Cell Culture (CC)
    • Intracellular Flow Cytometry (ICFC)
    • Affinity Measurement (AM)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Blocking Reagent (BR)
    • Flow Cytometry (FACS)
    • Immunoassay (IA)
    • Immunoprecipitation (IP)
    • Screening Assay (ScA)
    • Standard (STD)
    • Antibody Drug Assay (ADA)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Pig
    • Chicken
    • Macaca (Macaque)
    • Rabbit
    • Cow
    • Dog
    • Cynomolgus
    • Goat
    • Guinea Pig
    • Horse
    • Rhesus Monkey
    • Baboon
    • Callithrix jacchus
    • Cat
    • Chimpanzee
    • Fox
    • Hamster
    • Llama
    • Macaca nemestrina
    • Marmota monax
    • Monkey
    • Orcinus orca
    • Red Deer
    • Sheep
    • Squirrel Monkey
    • White-eyelid mangabey (Cercocebus)
    • Zebrafish (Danio rerio)
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Nur ohne Konservierungsmittel
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • CHO Cells
    • Mammalian Cells
    • Baculovirus infected Insect Cells
    • Human Cells
    • Bacteria
    • Wheat germ
  • Bindungsspezifität
    • AA 19-178
    • AA 1-178
    • AA 22-175
    • AA 19-175
    • AA 20-179
    • full length
    • partial
    • AA 17-174
    • AA 19-164
    • AA 20-177
    • AA 20-181
    • AA 21-181
    • AA 22-178
    • AA 23-180
  • Konjugat
    • His tag
    • Unkonjugiert
    • His tag,GST tag
    • GST tag
    • Fc Tag
    • TRX tag
    • Biotin,His-Avi Tag
    • His tag,MYC tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • His-B2M tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
    • Biologically Inactive
  • Grade
    • Animal-Free
    • GMP Grade
  • Hersteller
    • antibodies-online
    • CUSABIO
    • Signalway
    • Abbexa
    • Rockland
    • BioLegend
    • Biospes
    • ProSci
    • ACROBiosystems
    • BD Biosciences
    • Cloud-Clone
    • ITSI-Biosciences
    • OriGene
    • ProteoGenix

Aktuelle Publikationen für unsere IL-10 Proteine

Phadnis-Moghe, Crawford, Kaminski: "Suppression of human B cell activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin involves altered regulation of B cell lymphoma-6." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 144, Issue 1, pp. 39-50, (2015) (PubMed).

Larson, Hübner, Torrero, Morris, Brankin, Swierczewski, Davies, Vonakis, Mitre: "Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 9, pp. 4188-99, (2012) (PubMed).

Yang, Hirose, Takahashi, Kawakatsu, Takaiwa: "Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site." in: Plant biotechnology journal, Vol. 10, Issue 9, pp. 1035-45, (2012) (PubMed).

Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).

van der Vliet, Wang, Yue, Koon, Balk, Exley: "Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 11, pp. 7287-93, (2008) (PubMed).

Prussin, Metcalfe: "Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies." in: Journal of immunological methods, Vol. 188, Issue 1, pp. 117-28, (1996) (PubMed).

Schlaak, Schmitt, Hüls, Meyer zum Büschenfelde, Fleischer: "A sensitive and specific bioassay for the detection of human interleukin-10." in: Journal of immunological methods, Vol. 168, Issue 1, pp. 49-54, (1994) (PubMed).

Feng, Tang, Chang, Wilson: "Molecular cloning of rat cytokine synthesis inhibitory factor (IL-10) cDNA and expression in spleen and macrophages." in: Biochemical and biophysical research communications, Vol. 192, Issue 2, pp. 452-8, (1993) (PubMed).

Howard, OGarra, Ishida, de Waal Malefyt, de Vries: "Biological properties of interleukin 10." in: Journal of clinical immunology, Vol. 12, Issue 4, pp. 239-47, (1992) (PubMed).

Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 4, pp. 1172-6, (1991) (PubMed).

Aliase für IL-10 Proteine

interleukin 10 (IL10) Proteine
interleukin 10 (Il10) Proteine
CSIF Proteine
GVHDS Proteine
IL-10 Proteine
Il-10 Proteine
IL10A Proteine
IL10X Proteine
TGIF Proteine
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