IL-1 beta Proteine
(Interleukin 1, beta (IL1B))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
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IL1B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>95 % (SDS-PAGE)
SDS
IL1B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>98 % (SDS-PAGE)
IL1B
Spezies: Maus
Wirt: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
IL1B
Spezies: Cynomolgus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
IL1B
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % by SDS-PAGE and HPLC analyses.
Active
IL1B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL1B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
IL1B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
SDS, WB, ELISA
IL1B
Spezies: Kaninchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
IL1B
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
IL1B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
IL1B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
IL1B
Spezies: Meerschweinchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
IL1B
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL1B
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
IL1B
Spezies: Huhn
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
IL1B
Spezies: Rhesusaffen
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
IL1B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
IL1B
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
IL1B
Spezies: Schwein
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
Aktuelle Publikationen für unsere IL-1 beta Proteine
: "Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk." in: Frontiers in immunology, Vol. 10, pp. 746, (2020) (PubMed).: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." in: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).
: "Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5." in: Molecular vision, Vol. 21, pp. 360-77, (2015) (PubMed).
: "Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist." in: Oncogene, Vol. 34, Issue 19, pp. 2493-504, (2015) (PubMed).
: "Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 35, pp. 12835-40, (2014) (PubMed).
: "Activated microglia enhance neurogenesis via trypsinogen secretion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).
: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, (2011) (PubMed).
: "Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms." in: Annals of neurology, Vol. 70, Issue 6, pp. 943-54, (2011) (PubMed).
: "VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways." in: Blood, Vol. 111, Issue 7, pp. 3665-74, (2008) (PubMed).
: "Up-regulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2507-15, (2004) (PubMed).
Aliase für IL-1 beta Proteine
interleukin 1 beta (IL1B) Proteineinterleukin 1, beta (IL1B) Proteine
interleukin 1, beta (il1b) Proteine
interleukin 1 beta (Il1b) Proteine
IL-1 Proteine
IL-1 beta Proteine
IL-1B Proteine
Il-1b Proteine
IL-1b Proteine
IL-1BETA Proteine
IL-1beta Proteine
il1-b Proteine
IL1-BETA Proteine
IL1B Proteine
IL1beta Proteine
IL1F2 Proteine
zgc:111873 Proteine
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