HTR2C Produkte
(5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
Kategorien
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
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Ausgewählte HTR2C Kategorien
HTR2C Antikörper
High quality antibodies with extensive validation data.
HTR2C ELISA Kits
Reliable ELISA kits for a wide range of species.
HTR2C Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene HTR2C Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Horse, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB
Validierungen
- (6)
Kat. Nr.
ABIN2792274
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6257909
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN574008
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene HTR2C ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953364
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5674799
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5674800
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene HTR2C Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121620
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1307274
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3113303
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren HTR2C Produkten
: "Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 312, Issue 3, pp. L432-L439, (2017) (PubMed).: "An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist that Corrects Motor Stereotypy in Mouse Models." in: ACS chemical neuroscience, Vol. 6, Issue 7, pp. 1259-70, (2015) (PubMed).
: "Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model." in: Neurochemical research, Vol. 36, Issue 10, pp. 1785-92, (2011) (PubMed).
: "Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling." in: Frontiers in cellular neuroscience, Vol. 4, pp. 132, (2011) (PubMed).
: "Complex seizure disorder caused by Brunol4 deficiency in mice." in: PLoS genetics, Vol. 3, Issue 7, pp. e124, (2007) (PubMed).
: "Serotonin receptor 2C (HTR2C) and schizophrenia: examination of possible medication and genetic influences on expression levels." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 134B, Issue 1, pp. 84-9, (2005) (PubMed).
: "5-Hydroxytryptamine2C receptors on pudendal motoneurons innervating the external anal sphincter." in: Brain research, Vol. 1057, Issue 1-2, pp. 65-71, (2005) (PubMed).
Synonyme und alternative Namen zu HTR2C
5-hydroxytryptamine receptor 2C (HTR2C), 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c), 5-hydroxytryptamine receptor 2C (Htr2c), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog (htr2c.S), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 (htr2cl1), 5-hydroxytryptamine receptor 2C (LOC407134), 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (HTR2C), 5-HT-2C, 5-HT2C, 5-HT2cR, 5-ht2cr, 5-HTR2C, 5HT-1C, 5HT1c, 5HT2C, 5ht2c, 5HTR2C, HTR1C, Htr1c, si:dkey-24g18.2, SR1Bezeichner auf Proteinebene für HTR2C
- 5-HT-1C
- 5-HT-2C
- 5-HT1C
- 5-hydroxytryptamine receptor 1C
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor-1c
- serotonin 5-HT-2C receptor
- serotonin receptor 2C
- 5-HT2C receptor
- serotonin 1c receptor
- 5-hydroxytryptamine (serotonin) receptor 2C
- 5HT2C serotonin receptor
- 5-HT2C
- 5-alpha-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
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