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HSPG Produkte

(Heparan Sulphate Protoglycans (HSPG))
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].

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Ausgewählte HSPG Kategorien

HSPG Antikörper

High quality antibodies with extensive validation data.

HSPG ELISA Kits

Reliable ELISA kits for a wide range of species.

HSPG Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene HSPG Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow, Human, Mouse, Rat
Applikation ICC, IHC, IHC (fro), IHC (p), IP, WB
Validierungen
  • (2)
Kat. Nr. ABIN625887
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Cow, Human, Mouse, Rat
Applikation ICC, IHC (fro), IHC (p), IP, IHC, WB
Validierungen
  • (7)
Kat. Nr. ABIN335359
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, ELISA, WB
Validierungen
  • (1)
Kat. Nr. ABIN1173169
Menge 200 μL
Datenblatt Datenblatt

Empfohlene HSPG ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (8)
  • (1)
Kat. Nr. ABIN6954521
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6954522
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6963169
Menge 96 tests
Datenblatt Datenblatt

Empfohlene HSPG Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3009814
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7083183
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7083184
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren HSPG Produkten

Dekker, Veerhoek, Koning, van Leeuwen, Elbers, van den Brom, Vonk, Boer: "Postoperative microcirculatory perfusion and endothelial glycocalyx shedding following cardiac surgery with cardiopulmonary bypass." in: Anaesthesia, Vol. 74, Issue 5, pp. 609-618, (2019) (PubMed).

Gao, Zhang, Wang, Liu, He, Liu, Wang, Feng, Yang, Wang, Meng, Yan: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." in: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).

Alyoussef, Al-Gayyar: "Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro." in: Biomedicine & pharmacotherapy, Vol. 103, pp. 362-372, (2018) (PubMed).

Zhai, Wang, Zhang, Liang, Fu, Cui, Yang, Gong, Li, Yu, Xie, Yang, Yang, Gao: "Glioma targeting peptide modified apoferritin nanocage." in: Drug delivery, Vol. 25, Issue 1, pp. 1013-1024, (2018) (PubMed).

Nelson, Johansson, Tydén, Bodelsson: "Circulating syndecans during critical illness." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 5, pp. 468-475, (2017) (PubMed).

Arthur, McCall, Jolly, Kinsella, Kirk, Shelley: "Endothelial glycocalyx layer shedding following lung resection." in: Biomarkers in medicine, Vol. 10, Issue 10, pp. 1033-1038, (2016) (PubMed).

Martin, Schmitz, De Santis, Doemming, Haase, Hoeger, Heinbockel, Brandenburg, Marx, Schuerholz: "Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127584, (2016) (PubMed).

Jung, Fuernau, Muench, Desch, Eitel, Schuler, Adams, Figulla, Thiele: "Impairment of the endothelial glycocalyx in cardiogenic shock and its prognostic relevance." in: Shock (Augusta, Ga.), Vol. 43, Issue 5, pp. 450-5, (2015) (PubMed).

Tayel, Abd El Galil, Ebrahim, Ibrahim, El-Gayar, Al-Gayyar: "Suramin inhibits hepatic tissue damage in hepatocellular carcinoma through deactivation of heparanase enzyme." in: European journal of pharmacology, Vol. 728, pp. 151-60, (2014) (PubMed).

Al-ofi, Coffelt, Anumba: "Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients." in: Journal of reproductive immunology, Vol. 103, pp. 23-8, (2014) (PubMed).

Synonyme und alternative Namen zu HSPG

CD44 molecule (Indian blood group) (CD44), glypican 3 (GPC3), CD44 antigen (Cd44), CD44 molecule (Indian blood group) (Cd44), AU023126, AW121933, AW146109, CD44A, CDW44, CSPG8, ECMR-III, HCELL, HERMES, HUTCH-I, IN, LHR, Ly-24, MC56, MDU2, MDU3, METAA, MIC4, Pgp-1, Pgp1, RHAMM

Bezeichner auf Proteinebene für HSPG

  • CD44 antigen
  • GP90 lymphocyte homing/adhesion receptor
  • Hermes antigen
  • cell surface glycoprotein CD44
  • chondroitin sulfate proteoglycan 8
  • epican
  • extracellular matrix receptor III
  • hematopoietic cell E- and L-selectin ligand
  • heparan sulfate proteoglycan
  • homing function and Indian blood group system
  • hyaluronate receptor
  • phagocytic glycoprotein 1
  • ECMR-III
  • HUTCH-I
  • PGP-I
  • hermes antigen
  • lymphocyte antigen 24
  • phagocytic glycoprotein I
  • Cell surface glycoprotein CD44 (hyaluronate binding protein)
  • PGP-1
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