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Hepatitis B Virus Core Antigen Produkte

(Hepatitis B Virus Core Antigen (HBcAg))

Kategorien

Self assembles to form an icosahedral capsid. Most capsid appear to be large particles with a icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins. Entering capsid are transported along microtubules to the nucleus. Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta. Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153. Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm. Immature capsids get stucked in the basket. Capsids encapsulate the pre-genomic RNA and the P protein. Pre- genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm. The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions. {ECO:0000255|HAMAP-Rule:MF_04076}. Encapsidates hepatitis delta genome. {ECO:0000255|HAMAP- Rule:MF_04076}.

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Ausgewählte Hepatitis B Virus Core Antigen Kategorien

Hepatitis B Virus Core Antigen Antikörper

High quality antibodies with extensive validation data.

Hepatitis B Virus Core Antigen Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Hepatitis B Virus Core Antigen Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Hepatitis B Virus (HBV), Virus
Applikation ELISA, IHC (p), IF (p)
Validierungen
  • (1)
Kat. Nr. ABIN722991
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Hepatitis B Virus (HBV)
Applikation ELISA, LF, IA, D
Validierungen
Kat. Nr. ABIN7538983
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Hepatitis B Virus (HBV)
Applikation ELISA, LF, IA, D
Validierungen
Kat. Nr. ABIN7538984
Menge 1 mg
Datenblatt Datenblatt

Empfohlene Hepatitis B Virus Core Antigen ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Qualitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5025326
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Hepatitis B Virus Core Antigen Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Hepatitis B Virus (HBV)
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7478071
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Hepatitis B Virus (HBV)
Source Yeast (Pichia pastoris)
Validierungen
Kat. Nr. ABIN7478072
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Hepatitis B Virus (HBV)
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN573371
Menge 0.5 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Hepatitis B Virus Core Antigen Produkten

Dai, Chen, Yu, Zang, Tang et al.: "Immunization with lentiviral vector‑modified dendritic cells encoding ubiquitinated hepatitis B core antigen promotes Th1 differentiation and antiviral immunity by enhancing p38 MAPK and JNK ..." in: Molecular medicine reports, Vol. 18, Issue 5, pp. 4691-4699, (2019) (PubMed).

Ye, Tateno, Thi, Kakuni, Snead, Ishida, Barnard, Sofia, Shimada, Lee: "Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model." in: ACS infectious diseases, (2018) (PubMed).

Cao, Lazdina, Desombere, Vanlandschoot, Milich, Sällberg, Leroux-Roels: "Hepatitis B virus core antigen binds and activates naive human B cells in vivo: studies with a human PBL-NOD/SCID mouse model." in: Journal of virology, Vol. 75, Issue 14, pp. 6359-66, (2001) (PubMed).

Synonyme und alternative Namen zu Hepatitis B Virus Core Antigen

precore; HBe antigen; PreC; HBeAg; precore protein; external core antigen; HBeAg; p25 (C)

Bezeichner auf Proteinebene für Hepatitis B Virus Core Antigen

  • C0 uORF
  • Core antigen
  • Core protein
  • HBcAg
  • HBe antigen
  • HBeAg
  • PreC
  • capsid protein
  • external core antigen
  • p21.5
  • p25
  • pre-capsid protein
  • precore
  • precore protein
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