Hsc70 Proteine
(Heat Shock 70kDa Protein 8 (HSPA8))
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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19 Treffer
HSPA8
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
HSPA8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
HSPA8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
>90%
WB, SDS, ELISA, Func, AcA
Active
6 Referenzen
HSPA8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS-PAGE
SDS
1 image
HSPA8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
HSPA8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
HSPA8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
HSPA8
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
Spezies: Rind (Kuh)
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
Spezies: Huhn
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
HSPA8
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by reducing SDS-PAGE.
HSPA8
Spezies: Rind (Kuh)
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
HSPA8
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
HSPA8
Spezies: Huhn
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
HSPA8
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
HSPA8
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
Aktuelle Publikationen für unsere Hsc70 Proteine
: "Identification of a novel anti‑heat shock cognate 71 kDa protein antibody in patients with Kawasaki disease." in: Molecular medicine reports, Vol. 21, Issue 4, pp. 1771-1778, (2020) (PubMed).: "KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells." in: Molecular pharmacology, Vol. 88, Issue 1, pp. 121-30, (2015) (PubMed).
: "Identification of target antigens of naturally occurring autoantibodies in cerebrospinal fluid." in: Journal of proteomics, (2015) (PubMed).
: "A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane." in: PLoS pathogens, Vol. 11, Issue 8, pp. e1005086, (2015) (PubMed).
: "An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40." in: Nucleic acid therapeutics, Vol. 25, Issue 2, pp. 103-12, (2015) (PubMed).
: "STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity." in: Orphanet journal of rare diseases, Vol. 9, pp. 146, (2014) (PubMed).
: "Discovery of a novel type of autophagy targeting RNA." in: Autophagy, Vol. 9, Issue 3, pp. 403-9, (2013) (PubMed).
: "Heteromeric complexes of heat shock protein 70 (HSP70) family members, including Hsp70B', in differentiated human neuronal cells." in: Cell stress & chaperones, Vol. 15, Issue 5, pp. 545-53, (2010) (PubMed).
: "The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity." in: Journal of gastroenterology, Vol. 45, Issue 6, pp. 646-55, (2010) (PubMed).
: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).
Aliase für Hsc70 Proteine
heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) Proteineheat shock protein family A (Hsp70) member 8 (HSPA8) Proteine
heat shock protein family A (Hsp70) member 8 (Hspa8) Proteine
heat shock 70kDa protein 8 (HSPA8) Proteine
heat shock protein 8 (Hspa8) Proteine
heat shock protein 8 (hspa8) Proteine
2410008N15Rik Proteine
hsc54 Proteine
HSC54 Proteine
hsc70 Proteine
HSC70 Proteine
Hsc70 Proteine
hsc71 Proteine
HSC71 Proteine
Hsc71 Proteine
Hsc73 Proteine
hsp71 Proteine
HSP71 Proteine
hsp73 Proteine
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Hsp73 Proteine
hspa10 Proteine
HSPA10 Proteine
Hspa10 Proteine
lap1 Proteine
LAP1 Proteine
nip71 Proteine
NIP71 Proteine
wu:fb01g06 Proteine
wu:fi48b06 Proteine
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