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anti-Mouse (Murine) INHBA Antikörper:
anti-Rat (Rattus) INHBA Antikörper:
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Human Polyclonal INHBA Primary Antibody für BP, ELISA - ABIN258868
Sallustio, Costantino, Cox, Loverre, Divella, Rizzi, Schena: Human renal stem/progenitor cells repair tubular epithelial cell injury through TLR2-driven inhibin-A and microvesicle-shuttled decorin. in Kidney international 2013
Show all 3 Pubmed References
Human Polyclonal INHBA Primary Antibody für IHC, IHC (p) - ABIN4325951
Howley, Hussey, Link, Howe: Translational regulation of inhibin ?A by TGF? via the RNA-binding protein hnRNP E1 enhances the invasiveness of epithelial-to-mesenchymal transitioned cells. in Oncogene 2015
Cow (Bovine) Polyclonal INHBA Primary Antibody für WB - ABIN2785821
Ndiaye, Castonguay, Benoit, Silversides, Lussier: Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells. in Journal of ovarian research 2016
The present study demonstrated that EGF (zeige EGF Antikörper) controlled expression of three activin (zeige Actbeta Antikörper) subunits (inhbaa, inhbab and inhbb (zeige INHBB Antikörper)) in the follicle cells via diverse signaling pathways.
the hCG (zeige CGA Antikörper)-stimulated activin (zeige Actbeta Antikörper) betaA expression is dependent on the activation of the cAMP-PKA pathway
Activin (zeige Actbeta Antikörper) betaA is involved in promoting ovary and follicle growth, whereas activin betaB (zeige INHBB Antikörper) may have a tonic role throughout follicle development but becomes critical at the late stage of oocyte maturation and/or ovulation.
Activin (zeige Actbeta Antikörper) signaling through SMAD2 (zeige SMAD2 Antikörper)/3 in retinal progenitor cells regulates expression of transcription factors involved in cell type determination and promotes photoreceptor lineage specification.
Our study provided experimental and clinical evidence for the involvement of activin A and ALK4 (zeige ACVR1B Antikörper) in the pathophysiology of atrial fibrosis and atrial fibrillation
binding of SMAD2 (zeige SMAD2 Antikörper)/3, the intracellular effectors of activin (zeige Actbeta Antikörper) signaling, was significantly enriched at the Pmepa1 (zeige PMEPA1 Antikörper) gene, which encodes a negative feedback regulator of TGF-beta (zeige TGFB1 Antikörper) signaling in cancer cells, and at the Kdm6b (zeige Kdm6b Antikörper) gene, which encodes an epigenetic regulator promoting transcriptional plasticity.
These results suggest that prolonged exposure to hyperglycemia in the Ins2(Akita+/-) mice leads to progressive testicular disruption mediated by testicular activin (zeige Actbeta Antikörper) activity, rather than hormonal dysregulation.
This study tested the hypothesis that inhibins act in an autocrine manner on Leydig cells using a pre-pubertal Leydig cell line, TM3 (zeige TPM1 Antikörper), as a model of immature Leydig cells.
ENPP2 (zeige ENPP2 Antikörper) links Activin-A enhanced mTOR (zeige FRAP1 Antikörper) signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva
Mice with elevated levels of IL6 (zeige IL6 Antikörper) exhibited 8.1% weight loss after 9 weeks, whereas mice with elevated levels of activin A lost 11% of their body weight
a conserved role for activin (zeige Actbeta Antikörper) in enhancing adipokinetic hormone/glucagon (zeige GCG Antikörper) signaling and glycemic control, is reported.
Results indicate that activin (zeige Actbeta Antikörper) betaA has an important role outside of reproduction and development, specifically in digestion.
Activin A protects midbrain neurons in the 6-hydroxydopamine mouse model of Parkinson's disease.
pro-activin A share features seen in the pro-TGF-beta1 (zeige TGFB1 Antikörper) and pro-BMP-9 (zeige GDF2 Antikörper) structures.
Data suggest that activin A (INHBA) plays roles in inflammation, tissue repair, fibrosis, neoplastic activation of myofibroblasts, and leiomyoma development/growth. [REVIEW]
that high expression of INHBA was associated with poor response to therapy for de novo AML (zeige RUNX1 Antikörper), and it can serve as an adverse prognostic factor for this malignancy.
Activin-A may induce fibrosis in NASH (zeige SAMSN1 Antikörper) and alcoholic cirrhosis via activation of Kupffer cells to express pro-inflammatory molecules that promote HSC (zeige FUT1 Antikörper)-dependent fibrogenesis and could be a target for future anti-fibrotic therapies.
INHBA gene expression in gastric cancer tissue is considered a useful independent predictor of outcomes in patients with stage II/III gastric cancer who receive adjuvant chemotherapy with S-1.
Inhibin-B secretion and FSH (zeige BRD2 Antikörper) isoform distribution may play an integral part of follicular selection in the natural menstrual cycle. (Review)
The present study was undertaken to evaluate the distribution of the FSHB (zeige FSHB Antikörper) -211 G/T in men with normal or abnormal sperm parameters from Southern Italy to assess its functional relevance on the serum levels of reproductive hormones and on sperm parameters in men.
analysis of a novel SMAD (zeige SMAD1 Antikörper)-independent pathway linking enhanced activin B (zeige Actbeta Antikörper) signaling to reduced E-cadherin (zeige CDH1 Antikörper) expression and increased migration in type II endometrial cancer
Results confirm the prodevelopmental actions of activin A and indicate that CTGF (zeige CTGF Antikörper) may also function as an embryokine by regulating the number of ICM cells in the blastocyst and altering gene expression. Low concentrations of HGF (zeige HGF Antikörper) were inhibitory to development.
The expression of the components of the activin (zeige Actbeta Antikörper)-inhibin-follistatin (zeige FST Antikörper) system is altered in bovine cystic ovarian disease.
Results support a physiological role for granulosa-derived inhibin as an antagonist of bone morphogenetic protein action on thecal androgen synthesis.
activin (zeige Actbeta Antikörper) AB is a lignd for activin type IB receptor (zeige ACVR1B Antikörper) ALK7 (zeige ACVR1C Antikörper) and is responsible for activin (zeige Actbeta Antikörper)-mediated secretion of insulin (zeige INS Antikörper) from pancreatic beta cell line, MIN6.
An increased expression of Inhibin-beta A was found in oocytes collected from large and medium follicles compared with small follicles before or after in oocyte vitro maturation.
INHA (zeige INHA Antikörper) and INHB expression and cellular localization in porcine oocytes were studied.
results indicated that boar testis produces inhibin A and inhibin B during the infantile period but inhibin A is the predominant form towards puberty and molecular weight forms of inhibin and the sites of production change with testicular development
This is the first report on INHBA as an associated candidate gene with the LSM of stallions and the paternal and embryonic component of BVs for the pregnancy rate per oestrus.
The result showed that AA genotype had remarkable litter size at P1 locus in the three goat breeds (P < 0.05). Therefore, these results suggest that INHA (zeige INHA Antikörper) gene is a strong candidate gene that affects litter size in goats.
Sequence comparison showed that three base changes in INHA (zeige INHA Antikörper)(two amino acid substitutions), and three base changes in INHBA,(one amino acid substitution). No difference seen in INHA (zeige INHA Antikörper) or INHBA mRNA expression level in the follicle of the two goat breeds.
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
inhibin, beta A
, activin beta A
, activin beta A1
, inhibin beta A
, inhibin, beta A (activin A, activin AB alpha polypeptide)
, activin A
, inhibin beta A chain-like
, activin beta-A chain
, inhibin beta A chain
, FSH-releasing protein
, Inhibin, beta-1
, erythroid differentiation factor
, erythroid differentiation protein
, follicle-stimulating hormone-releasing protein
, inhibin beta-subunit
, inhibin beta A subunit
, inhibin beta-A-subunit