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anti-Human GHRH Antikörper:
anti-Mouse (Murine) GHRH Antikörper:
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Cow (Bovine) Polyclonal GHRH Primary Antibody für RIA, ELISA - ABIN2473907
Thomas, Amstalden, Hallford, Silver, Garcia, Keisler, Williams: Dynamics of GHRH in third-ventricle cerebrospinal fluid of cattle: relationship with serum concentrations of GH and responses to appetite-regulating peptides. in Domestic animal endocrinology 2009
GHRH and GHRH-R (zeige GHRHR Antikörper) are expressed in human adipocytes and are negatively associated; GHRH at low doses may exert an anti-obesity effect by inhibiting HMSC differentiation in adipocytes and by increasing adipocyte lipolysis in an autocrine or paracrine pathway; these effects are mediated by GH and GH-R
GHRH stimulates a ligand-independent activation of EGFR (zeige EGFR Antikörper) involving at least cAMP/PKA and Src (zeige SRC Antikörper) family signaling pathways
GHRH analogs of the Miami series powerfully suppress tumor growth, but have only a weak endocrine GH inhibitory activity. The suppression of tumor growth could be induced in part by the downregulation of
Report a high rate of GHRH-R (zeige GHRHR Antikörper) and GHRH expression in apocrine breast carcinomas.
GHRH and GHRH-R (zeige GHRHR Antikörper) loops are involved in placental choriocarcinoma cell line viability and apoptosis through Akt (zeige AKT1 Antikörper) and eIF2a (zeige EIF2S1 Antikörper) pathways.
GHRH excess and blockade in X-LAG (zeige STMN1 Antikörper) syndrome
case Report: multiple endocrine neoplasia type 1 family characterized by primary hyperparathyroidism, in association with acromegaly because of ectopic GHRH secretion by a pancreatic neuroendocrine tumor in a young man.
After 20 weeks of GHRH administration, gamma-aminobutyric acid levels are increased in all brain regions, N-acetylaspartylglutamate levels are increased in the dorsolateral frontal cortex, and myoinositol levels are decreased in the posterior cingulate.
The pathomechanisms involved in the genetic defects at both ends of the GHRH-IGF-1 (zeige IGF1 Antikörper) axis.
Pretreatment with GHRH for 12 days could restore pituitary responsiveness to GHRH either in healthy aged men and growth hormone-deficient adult patients.
Concentrations of GHRH in CSF (zeige CSF2 Antikörper) were weakly correlated with serum concentrations of growth hormone (GH (zeige GH1 Antikörper)); 58% of the GH pulses were preceded by a pulse of GHRH and 90% of the GHRH pulses occurred within 20 min preceding a pulse of GH.
polymorphisms in GHRH might be one of the important genetic factors that influence carcass yield in beef cattle
Growth hormone-releasing hormone agonist markedly improve therapeutic angiogenesis in hindlimb ischemia by increasing the viability and mobility of mesenchymal stem cells.
The increased food intake observed in GHRH ablated animals is associated with increased locomotor and thermogenic activity.
In male mice GHRH deficiency brings about an increased physical activity and decreased anxiety- and depression-related behaviour, possibly related to increased TRH (zeige TRH Antikörper) and decreased NE levels in the brain.
These data suggest that ghrelin (zeige GHRL Antikörper) increases GHRH neuron excitability by increasing action potential firing rates and decreasing the strength of GABA inputs, leading to enhanced GHRH release; and that obestatin counteracts ghrelin (zeige GHRL Antikörper) actions.
GHRH stimulated the NF-kappa b (zeige NFKB1 Antikörper) transcription factor, which is not only known to activate angiogenic factors but also the expression of genes involved in encoding enzymes in the prostaglandin-synthesis pathway such as COX-2 (zeige COX2 Antikörper) and the iNOS (zeige NOS2 Antikörper)
Findings establish a novel ontogenetic profile for GHRH neurons and suggest previously undiscovered roles for peripubertal gonadal factors in establishing population size in both sexes.
treatment with a GHRH antagonist has positive effects on some aspects of aging, including an increase in telomerase activity.
Review. Growth hormone-releasing hormone (GHRH) is a hypothalamic hormone that is essential for normal expansion of the somatotrope lineage during pituitary development.
GHRH plays a crucial role in the development of experimental autoimmune encephalomyelitis.
Efficient production of mature GHRH from pro-GHRH is a stepwise process mediated predominantly by furin (zeige FURIN Antikörper) at the N-terminal cleavage site followed by PC1/3 (zeige PCSK1 Antikörper) at the C terminus
The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
growth hormone-releasing factor
, growth hormone-releasing hormone