GHRH Antikörper (N-Term)

Produktnummer ABIN392174

Der Kaninchen Polyklonal anti-GHRH Antikörper wird verwendet zum Nachweis von GHRH in Proben von Human. Er wurde validiert für WB, IHC (p) und IF.

Kurzübersicht für GHRH Antikörper (N-Term) (ABIN392174)

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GHRH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Klon: RB14533

Produktdetails anti-GHRH Antikörper

Bindungsspezifität: AA 8-34, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GHRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-34 amino acids from the N-terminal region of human GHRH.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu GHRH

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Andere Bezeichnung: GHRH

Hintergrund: GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this protein are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Molekulargewicht: 12447

Gen-ID: 2691

NCBI Accession: NP_001171660, NP_066567

UniProt: P01286

Pathways: Hormone Transport, Hormone Activity, cAMP Metabolic Process