anti-CRYM (CRYM) Antikörper

Bezeichnung:: anti-Crystallin, mu Antikörper (CRYM)

Auf www.antikoerper-online.de finden Sie aktuell 74 Crystallin, mu (CRYM) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CRYM Kits (10) und CRYM Proteine (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 100 CRYM Produkte verfügbar.

Synonyme:: CRYM, DFNA40, THBP, zgc:158843

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	CRYM	1428	Q14894
	CRYM	12971	O54983
	CRYM	117024	Q9QYU4
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anti-Human CRYM Antikörper:

anti-Mouse (Murine) CRYM Antikörper:

anti-Rat (Rattus) CRYM Antikörper:

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Am meisten referenzierte anti-CRYM Antikörper

Mouse (Murine) Polyclonal CRYM Primary Antibody für WB - ABIN1881230 : Al-Kafaji, Malik: Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells. in Biochemical and biophysical research communications 2010 (PubMed)
Show all 4 Pubmed References
Human Monoclonal CRYM Primary Antibody für IHC (p), IP - ABIN560481 : Reed, Corse, Porter, Flanigan, Bloch: Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy. in Experimental neurology 2007 (PubMed)
Show all 3 Pubmed References

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Human Crystallin, mu (CRYM) Interaktionspartner

These findings confirm that, mechanistically, ketimine reductase/CRYM acts as a classical imine reductase and may explain the finding of bound pyruvate in the crystallized protein.
ketimine reductase is a key enzyme in the pipecolate pathway, which is the main lysine degradation pathway in the brain
The expression of mu-crystallin was regulated through the AP-1 (zeige FOSB Antikörper) site in the promoter.
Its ketimine reductase activity is strongly inhibited by thyroid hormones.
This is the first report linking hyperglycemia with thyroid hormone (zeige PTH Antikörper) binding protein CRYM and suggests that the role of CRYM in diabetic complications should be further investigated.
Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues
CRYM is a novel androgen-regulated gene whose expression is elevated in prostate cancer but down-regulated in castration therapy-resistant tumors.

Mouse (Murine) Crystallin, mu (CRYM) Interaktionspartner

The results demonstrated that Crym is a crucial regulator of muscle plasticity, controlling metabolic and contractile properties of myofibers, and thus the selective inactivation of Crym may be a potential therapeutic target for muscle-wasting diseases.
Reduction of Crym expression in Huntington's disease (HD) could render striatal neurons more susceptible to mutant huntingtin (zeige HTT Antikörper) suggesting that Crym may be a key determinant of the vulnerability of the striatum.
CRYM expression increases and sustains the T3 responsiveness of genes in cells, especially with alteration of the pericellular T3 concentration.
Comparison of the apo and NADPH forms reveals a rearrangement of the protein upon NADPH binding that reduces the degrees of freedom of several residues and traps the conformation of the binding pocket in a more T3 competent state.
The expression of mu-crystallin was regulated through the AP-1 (zeige JUN Antikörper) site in the promoter.
CRYM plays an important role in the development of the second peak of murine EIU.
Disruption of the CRYM gene decreases T(3) concentrations in tissues and serum without alteration of peripheral T(3) action in vivo.

CRYM Antigen-Profil

Beschreibung des Gens

Crystallins are separated into two classes and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with CRYM

crystallin mu (CRYM) Antikörper
crystallin, mu (crym) Antikörper
Cro/Cl family transcriptional regulator (EAMY_RS27495) Antikörper
crystallin mu L homeolog (crym.L) Antikörper
crystallin mu (crym) Antikörper
crystallin, mu (Crym) Antikörper

CRYM Antikörper
DFNA40 Antikörper
THBP Antikörper
zgc:158843 Antikörper

Bezeichner auf Proteinebene für anti-Crystallin, mu (CRYM) Antikörper

crystallin, mu , mu-crystallin homolog , mu-crystallin homolog-like , mu-crystallin-like protein , NADP-regulated thyroid-hormone binding protein , ketimine reductase , thiomorpholine-carboxylate dehydrogenase , NADP-regulated thyroid-hormone-binding protein , CDK108

GENE ID	SPEZIES
427008	Gallus gallus
479818	Canis lupus familiaris
697588	Macaca mulatta
742586	Pan troglodytes
791205	Danio rerio
8913325	Erwinia amylovora CFBP1430
100101313	Xenopus laevis
100125176	Xenopus (Silurana) tropicalis
100388738	Callithrix jacchus
100454622	Pongo abelii
100528988	Ictalurus punctatus
1428	Homo sapiens
12971	Mus musculus
117024	Rattus norvegicus
505167	Bos taurus

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Show all anti-Crystallin, mu (CRYM) Antikörper with Pubmed References

Human Crystallin, mu (CRYM) Interaktionspartner

Mouse (Murine) Crystallin, mu (CRYM) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with CRYM

Bezeichner auf Proteinebene für anti-Crystallin, mu (CRYM) Antikörper