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CRSP-1 is considered to be a new regulator for the urinary ion excretion and renal epithelial cell growth
CRSP1 and CRSP2 have almost identical sequences whereas CRSP3 retains less similarity with the above genes.
The results suggest that C12orf39, CSTA, and CALCB are novel ATF4 target genes, and that C12orf39 promoter activity is activated by ATF4 through amino acid response element.
Keratinocyte-derived CGRPbeta may modulate epidermal homeostasis through autocrine/paracrine signaling and may contribute to chronic pain under pathological conditions.
CGRP and ADM are two differentially regulated novel adipose tissue secretion factors exerting autocrine/paracrine roles.
Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells.
activation of periosteal mineralizing surfaces in response to mechanical loading of bone is CGRPalpha-dependent in vivo.
These results indicate that CGRP signaling through CLR/RAMP1 receptors plays a crucial role in the regulation of both blood pressure by vascular relaxation and proinflammatory cytokine production from dendritic cells.
gene expression of calcitonin gene-related peptide beta in mouse brain, liver, kidney, heart, & testis at embryonic day 14, 17, postnatal day 1, 7, and adult. found mainly in brain. one expression peak at E17, the other at P7. also C cells of e17 thyroid.
A close association of betaCGRP-containing dysmorphic dendritic structures with processes of activated astrocytes suggests that betaCGRP may function as a motor neuron-derived signaling molecule for astrocyte activation in amyotrophic lateral sclerosis
may play a role in regulating transduction of sensory and motor information
calcitonin receptor-stimulating peptide 1
, calcitonin receptor-stimulating peptide-1
, calcitonin-related polypeptide, beta
, calcitonin-related polypeptide beta
, Calcitonin receptor-stimulating peptide 1
, beta-type CGRP
, calcitonin 2
, calcitonin gene-related peptide 2
, calcitonin gene-related peptide II
, calcitonin gene related peptide II