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Histone H2A Produkte

(Histone H2A)
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development.

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Ausgewählte Histone H2A Kategorien

Histone H2A Antikörper

High quality antibodies with extensive validation data.

Histone H2A ELISA Kits

Reliable ELISA kits for a wide range of species.

Histone H2A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Histone H2A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IF, IHC, WB
Validierungen
  • (7)
Kat. Nr. ABIN7267725
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IF, IHC, IP, WB
Validierungen
  • (7)
Kat. Nr. ABIN7267726
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, WB
Validierungen
  • (5)
Kat. Nr. ABIN7267724
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Histone H2A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956582
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Competition ELISA
Validierungen
Kat. Nr. ABIN2112539
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Histone H2A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3126014
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7123346
Menge 50 μg
Datenblatt Datenblatt
Reaktivität CHO cells
Source Insect Cells
Validierungen
Kat. Nr. ABIN7126067
Menge 0.5 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Histone H2A Produkten

Diaz, Engle, Tice, Melis, Montenegro, Rodriguez-Canales, Hanson, Emmert-Buck, Bock, Moore, Zamboni, Govindarajan, Kleiner, Farci: "Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma." in: Molecular cancer research : MCR, Vol. 16, Issue 9, pp. 1406-1419, (2018) (PubMed).

Young, Hillyer, Hokamp, Fitzpatrick, Konstantinov, Welty, Ness, Werner-Washburne, Fleming, Osley: "Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast." in: BMC genomics, Vol. 18, Issue 1, pp. 107, (2017) (PubMed).

Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).

Ferrari, Bruhn, Peretti, Cassani, Carotenuto, Elgendy, Shubassi, Lucca, Bermejo, Varasi, Minucci, Longhese, Foiani: "PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response." in: Molecular cell, Vol. 67, Issue 2, pp. 266-281.e4, (2017) (PubMed).

Baron, von Schubert, Cubizolles, Siemeister, Hitchcock, Mengel, Schröder, Fernández-Montalván, von Nussbaum, Mumberg, Nigg: "Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524." in: eLife, Vol. 5, (2017) (PubMed).

Bekier, Mazur, Rashid, Taylor: "Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores." in: Nature communications, Vol. 6, pp. 6775, (2015) (PubMed).

Alvarez-Saavedra, De Repentigny, Lagali, Raghu Ram, Yan, Hashem, Ivanochko, Huh, Yang, Mears, Todd, Corcoran, Bassett, Tokarew, Kokavec, Majumder, Ioshikhes, Wallace, Kothary, Meshorer, Stopka et al.: "Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. ..." in: Nature communications, Vol. 5, pp. 4181, (2014) (PubMed).

Jha, Strahl: "An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair." in: Nature communications, Vol. 5, pp. 3965, (2014) (PubMed).

Fleming, Beggs, Church, Tsukihashi, Pennings: "The yeast Cyc8-Tup1 complex cooperates with Hda1p and Rpd3p histone deacetylases to robustly repress transcription of the subtelomeric FLO1 gene." in: Biochimica et biophysica acta, Vol. 1839, Issue 11, pp. 1242-55, (2014) (PubMed).

Synonyme und alternative Namen zu Histone H2A

Histone H2A variant (His2Av), putative histone H2A (LMJF_17_0280), histone H2A (H2AX), histone cluster 1 H2A family member F (Hist1h2af), histone H2A-like (LOC100425378), histone cluster 1, H2af (Hist1h2af), histone2A1 (his2a1), histone cluster 1, H2A, III (HIST1H2A3), histone cluster 1, H2ac (HIST1H2AC), histone H2A (h2a-A), 5499, CG5499, DDBDRAFT_0205974, DDBDRAFT_0216271, DDB_0205974, DDB_0216271, Dmel\\CG5499, gamma-H2Av, gamma-HIS2AV, gamma-His2Av, gammaH2Av, H2A, H2a-221, H2A-III, H2A.F/Z, H2a.V, H2A.X, H2A.Z, H2AV, H2Av, H2av, H2AvD, H2avD, h2AvD, H2AV_DROM, H2AX, H2AZ, HIS, His, his, His2, HIS2AV, His2AV, HIS2AVD, His2AvD, HisH2Av, Hist, HIST1H2AA, Hist2av, l(3)05146, l(3)97Dd, l(3)810, l(3)L1602, RGD1564767

Bezeichner auf Proteinebene für Histone H2A

  • CG5499-PA
  • CG5499-PB
  • H2A variant
  • His2Av-PA
  • His2Av-PB
  • Histone-2A
  • Histone2Av
  • histone
  • histone 2A variant
  • histone H2A variant
  • histone H2Av
  • histone variant H2Av
  • histone2A
  • histone2AvD
  • histone H2A
  • Histone H2a
  • histone 1, H2af
  • histone H2A type 1-F
  • histone H2a (aa 92-128)
  • CL2029_4
  • CL2029_4(696)
  • CL2029_4_ov
  • CL2029_4b
  • H2A
  • Zm.ov5
  • p-Zm.ov5
  • H2A histone
  • histone H2A-III
  • histone H2A type 1-C
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