Hect E3 Ubiquitin Ligase Antikörper (AA 1-100)
Kurzübersicht für Hect E3 Ubiquitin Ligase Antikörper (AA 1-100) (ABIN1713527)
Target
Reaktivität
Wirt
Klonalität
Applikation
-
-
Bindungsspezifität
- AA 1-100
-
Verwendungszweck
- HECT E3 ubiquitin ligase Antibody
-
Kreuzreaktivität
- Human, Ratte
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human HECT E3 ubiquitin ligase
-
Isotyp
- IgG
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- Hect E3 Ubiquitin Ligase (LOC662402)
-
Andere Bezeichnung
- HECT E3 ubiquitin ligase
-
Hintergrund
-
Synonyms: CEB1, CEBP1, Cyclin E binding protein 1, Cyclin-E-binding protein 1, E3 ISG15--protein ligase HERC5, HECT domain and RCC1 like domain containing protein 5, HECT domain and RCC1-like domain-containing protein 5, Hect domain and RLD 5, HECT E3 ubiquitin ligase, HERC5, HERC5_HUMAN, Herc6.
Background: HECT E3 ubiquitin ligase is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
-
Gen-ID
- 51191
Target
-
