Hect E3 Ubiquitin Ligase Antikörper (AA 1-100)
Kurzübersicht für Hect E3 Ubiquitin Ligase Antikörper (AA 1-100) (ABIN1713527)
Target
Reaktivität
Wirt
Klonalität
Applikation
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Bindungsspezifität
- AA 1-100
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Kreuzreaktivität
- Ratte
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Homologie
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human HECT E3 ubiquitin ligase
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- Hect E3 Ubiquitin Ligase (LOC662402)
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Andere Bezeichnung
- HECT E3 ubiquitin ligase
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Hintergrund
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Synonyms: CEB1, CEBP1, Cyclin E binding protein 1, Cyclin-E-binding protein 1, E3 ISG15--protein ligase HERC5, HECT domain and RCC1 like domain containing protein 5, HECT domain and RCC1-like domain-containing protein 5, Hect domain and RLD 5, HECT E3 ubiquitin ligase, HERC5, HERC5_HUMAN, Herc6.
Background: HECT E3 ubiquitin ligase is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
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Gen-ID
- 51191
Target
-
