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HAS1 Proteine

(Hyaluronan Synthase 1 (HAS1))
Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS1 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to the hasA gene product of Streptococcus pyogenes, a glycosaminoglycan synthetase (DG42) from Xenopus laevis, and a recently described murine hyaluronan synthase. [provided by RefSeq, Jul 2008].

9 Treffer

custom-made HAS1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7557723
 
custom-made HAS1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7554134
 
HAS1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7404638
 
HAS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
Produktnummer ABIN7396481
 
custom-made HAS1 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Produktnummer ABIN3123028
 
custom-made HAS1 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Produktnummer ABIN3117112
 
HAS1 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3009895
 
HAS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, WB
Produktnummer ABIN6120523
 
HAS1 Spezies: Ratte Wirt: Yeast (Saccharomyces Cerevisiae) SDS, WB
Produktnummer ABIN6120077
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Immunoprecipitation (IP)
  • Reaktivität
    • Human
    • Rat
    • Mouse
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Yeast (Saccharomyces Cerevisiae)
  • Bindungsspezifität
    • AA 1-578
    • AA 1-583
    • AA 160-416
    • AA 164-421
  • Konjugat
    • His tag
    • Unkonjugiert
    • Strep Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online
    • Abbexa

Aliase für HAS1 Proteine

hyaluronan synthase 1 (has1) Proteine
hyaluronan synthase 1 (HAS1) Proteine
hyaluronan synthase 1 (Has1) Proteine
hyaluronan synthase 1 S homeolog (has1.S) Proteine
dg42 Proteine
HAS Proteine
shas1 Proteine
Xhas1 Proteine
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