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GRP78 Proteine

(Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010].

25 Treffer

HSPA5 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Produktnummer ABIN3009776
 
HSPA5 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2723102
 
HSPA5 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant SDS, WB
Produktnummer ABIN6123352
 
HSPA5 Spezies: Ratte Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN7584759
 
HSPA5 Spezies: Schwein Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1472489
 
  • Typ Protein
    • Protein
  • Anwendung
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Functional Studies (Func)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Pig
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • Hi-5 Cells
    • Yeast
    • HEK-293 Cells
    • Wheat germ
  • Bindungsspezifität
    • AA 19-654
    • AA 20-650
    • AA 20-655
    • AA 261-470
    • AA 1-262
    • AA 25-293
    • AA 260-469
    • full length
    • partial
  • Konjugat
    • His tag
    • Unkonjugiert
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biologische Aktivität
    • Biologically Active
  • Hersteller
    • antibodies-online
    • Abbexa
    • CUSABIO
    • OriGene
    • Signalway

Aktuelle Publikationen für unsere GRP78 Proteine

Chen, Zhang, Yu, Chong, Yoshioka, Ge: "Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction." in: Cell death and differentiation, Vol. 21, Issue 5, pp. 797-810, (2014) (PubMed).

Čiplys, Aučynaitė, Slibinskas: "Generation of human ER chaperone BiP in yeast Saccharomyces cerevisiae." in: Microbial cell factories, Vol. 13, pp. 22, (2014) (PubMed).

Kosakowska-Cholody, Lin, Srideshikan, Scheffer, Tarasova, Acharya: "HKH40A downregulates GRP78/BiP expression in cancer cells." in: Cell death & disease, Vol. 5, pp. e1240, (2014) (PubMed).

Bruchmann, Roller, Walther, Schäfer, Lehmusvaara, Visakorpi, Klocker, Cato, Maddalo: "Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis." in: BMC cancer, Vol. 13, pp. 96, (2013) (PubMed).

Ding, Li, Wu, Yang, Luo, Xie, Druey, Zajac, Hsu, Mountz: "IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 4, pp. 1614-24, (2013) (PubMed).

Maddalo, Neeb, Jehle, Schmitz, Muhle-Goll, Shatkina, Walther, Bruchmann, Gopal, Wenzel, Ulrich, Cato: "A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death." in: PLoS ONE, Vol. 7, Issue 10, pp. e45690, (2012) (PubMed).

Taylor, Gercel-Taylor, Parker: "Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer." in: Gynecologic oncology, Vol. 115, Issue 1, pp. 112-20, (2009) (PubMed).

Zwang, Hoffert, Pisitkun, Moeller, Fenton, Knepper: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).

Ting, Lee: "Human gene encoding the 78,000-dalton glucose-regulated protein and its pseudogene: structure, conservation, and regulation." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 4, pp. 275-86, (1988) (PubMed).

Aliase für GRP78 Proteine

78 kDa glucose-regulated protein (CpipJ_CPIJ003550) Proteine
heat shock protein family A (Hsp70) member 5 (HSPA5) Proteine
78 kDa glucose-regulated protein (grp78) Proteine
BiP/GRP78 (LOC100533358) Proteine
glucose-regulated protein 78 (BiP/grp78) Proteine
glucose-regulated protein 78 (Tc00.1047053506585.40) Proteine
glucose-regulated protein 78 (Tb11.02.5450) Proteine
glucose-regulated protein 78 (Tb11.02.5500) Proteine
putative glucose-regulated protein 78 (LMJF_28_1200) Proteine
Hsp70 family ATPase KAR2 (KAR2) Proteine
78 kDa glucose-regulated protein (LOC100135840) Proteine
heat shock protein family A (Hsp70) member 5 S homeolog (hspa5.S) Proteine
heat shock 70 kDa protein 5a (hspa5) Proteine
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5) Proteine
heat shock protein family A (Hsp70) member 5 (Hspa5) Proteine
heat shock protein 5 (Hspa5) Proteine
heat shock protein family A member 5 (Hspa5) Proteine
heat shock protein 5 (hspa5) Proteine
AL022860 Proteine
AU019543 Proteine
baffled Proteine
BiP Proteine
BIP Proteine
Bip Proteine
cb865 Proteine
D2Wsu17e Proteine
D2Wsu141e Proteine
fb60h09 Proteine
fi36d04 Proteine
GRP-78 Proteine
GRP78 Proteine
grp78 Proteine
Grp78 Proteine
Hsce70 Proteine
hspa5a Proteine
mBiP Proteine
MIF2 Proteine
SEZ-7 Proteine
Sez7 Proteine
wu:fb60h09 Proteine
wu:fi36d04 Proteine
zgc:55994 Proteine
zgc:77606 Proteine
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