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GLI2 Produkte

(GLI Family Zinc Finger 2 (GLI2))

Kategorien

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008].

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Ausgewählte GLI2 Kategorien

GLI2 Antikörper

High quality antibodies with extensive validation data.

GLI2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene GLI2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC, WB
Validierungen
  • (23)
  • (6)
  • (2)
Kat. Nr. ABIN2777474
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, IF, ELISA, WB
Validierungen
  • (5)
Kat. Nr. ABIN3031039
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation IHC, ELISA, WB
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN129624
Menge 100 μg
Datenblatt Datenblatt

Empfohlene GLI2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6967001
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5594596
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN2870159
Menge 96 tests
Datenblatt Datenblatt

Empfohlene GLI2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3092748
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3134900
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren GLI2 Produkten

Gonnissen, Isebaert, Perneel, McKee, Van Utterbeeck, Lerut, Verrill, Bryant, Joniau, Muschel, Haustermans: "Patched 1 Expression Correlates with Biochemical Relapse in High-Risk Prostate Cancer Patients." in: The American journal of pathology, Vol. 188, Issue 3, pp. 795-804, (2019) (PubMed).

Mazzone, Gibbons, Eisenman, Strege, Zheng, DAmato, Ordog, Fernandez-Zapico, Farrugia: "Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6632-6642, (2019) (PubMed).

Zhu, Xia, Shen, Zhao, Gu, Bouamar, Wang, Sun, Zhu: "Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo." in: Laboratory investigation; a journal of technical methods and pathology, (2018) (PubMed).

Gonnissen, Isebaert, McKee, Dok, Haustermans, Muschel: "The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo." in: Oncotarget, Vol. 7, Issue 51, pp. 84286-84298, (2018) (PubMed).

Gonnissen, Isebaert, Perneel, McKee, Verrill, Bryant, Van Utterbeeck, Lerut, Haustermans, Muschel: "Tissue microarray analysis indicates hedgehog signaling as a potential prognostic factor in intermediate-risk prostate cancer." in: BMC cancer, Vol. 17, Issue 1, pp. 634, (2018) (PubMed).

Gonnissen, Isebaert, McKee, Muschel, Haustermans: "The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells." in: International journal of molecular sciences, Vol. 18, Issue 2, (2017) (PubMed).

Wu, Ingram, Tolosa, Vera, Li, Kim, Ma, Spyropoulos, Beharry, Huang, Fernandez-Zapico, Cai: "Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis." in: The Journal of biological chemistry, Vol. 291, Issue 49, pp. 25749-25760, (2016) (PubMed).

Enzenhofer, Parzefall, Haymerle, Schneider, Kadletz, Heiduschka, Pammer, Oberndorfer, Wrba, Loader, Grasl, Perisanidis, Erovic: "Impact of Sonic Hedgehog Pathway Expression on Outcome in HPV Negative Head and Neck Carcinoma Patients after Surgery and Adjuvant Radiotherapy." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167665, (2016) (PubMed).

Won, Kim, Lim, Sung, Kim, Park, Lee, Choi: "Autophagy is related to the hedgehog signaling pathway in human gastric adenocarcinoma: prognostic significance of Beclin-1 and Gli2 expression in human gastric adenocarcinoma." in: Pathology, research and practice, Vol. 211, Issue 4, pp. 308-15, (2015) (PubMed).

Martinez, Kobayashi, Krishnan, Webber, Christie, Guo, Singh, Zochodne: "Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen." in: Experimental neurology, Vol. 271, pp. 493-505, (2015) (PubMed).

Synonyme und alternative Namen zu GLI2

GLI family zinc finger 2 (GLI2), GLI family zinc finger 2 (Gli2), GLI-Kruppel family member GLI2 (Gli2), AW546128, GLI2/GLI4, GLI3, HPE9, THP1, THP2

Bezeichner auf Proteinebene für GLI2

  • GLI-Kruppel family member GLI2
  • glioma-associated oncogene family zinc finger 2
  • oncogene GLI2
  • tax helper protein 1
  • tax helper protein 2
  • tax-responsive element-2 holding protein
  • tax-responsive element-25-bp sequence binding protein
  • zinc finger protein GLI2
  • Zn finger transcription factor
  • zinc finger protein GLI3
  • Tax helper protein
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