GIT2 Produkte
(G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
Kategorien
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008].
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Ausgewählte GIT2 Kategorien
GIT2 Antikörper
High quality antibodies with extensive validation data.
GIT2 ELISA Kits
Reliable ELISA kits for a wide range of species.
GIT2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene GIT2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN564230
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IP
Validierungen
- (5)
Kat. Nr.
ABIN564231
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (4)
Kat. Nr.
ABIN523246
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene GIT2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5648198
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6217294
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6217291
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene GIT2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7547979
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7561681
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1355123
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren GIT2 Produkten
: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." in: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).: "VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis." in: PLoS ONE, Vol. 7, Issue 5, pp. e36911, (2012) (PubMed).
: "GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats." in: PLoS ONE, Vol. 7, Issue 5, pp. e36975, (2012) (PubMed).
: "Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses." in: PLoS ONE, Vol. 5, Issue 12, pp. e14352, (2010) (PubMed).
Synonyme und alternative Namen zu GIT2
GIT ArfGAP 2 (GIT2), G protein-coupled receptor kinase interacting ArfGAP 2 (git2), G protein-coupled receptor kinase interacting ArfGAP 2a (git2a), G protein-coupled receptor kinase-interactor 2 (Git2), GIT ArfGAP 2 (Git2), G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog (git2.L), G protein-coupled receptor kinase interacting ArfGAP 2b (git2b), 1500036H07Rik, 5830420E16Rik, 6430510B20Rik, 9630056M03Rik, B230104M05Rik, CAT-2, cat-2, CAT2, git2, mKIAA0148, si:dkey-234h16.4, xgit2, zgc:158416Bezeichner auf Proteinebene für GIT2
- ARF GAP GIT2
- ARF GTPase-activating protein GIT2
- G protein-coupled receptor kinase-interactor 2
- GRK-interacting protein 2
- cool-associated, tyrosine phosphorylated protein 2
- cool-interacting tyrosine-phosphorylated protein 2
- G protein-coupled receptor kinase interactor 2
- ARF GTPase activating protein 2
- cool associated tyrosine phosphorylated-2
- G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog
- G protein-coupled receptor kinase interacting ArfGAP 2
- G protein-coupled receptor kinase interactor 2b
- tyrosine-phosphorylated protein CAT-2
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