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FTH1 Produkte

(Ferritin, Heavy Polypeptide 1 (FTH1))
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Ausgewählte FTH1 Kategorien

FTH1 Antikörper

High quality antibodies with extensive validation data.

FTH1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FTH1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FTH1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7435313
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (9)
Kat. Nr. ABIN7437164
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Pig
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7440041
Menge 100 μL
Datenblatt Datenblatt

Empfohlene FTH1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (5)
  • (1)
Kat. Nr. ABIN6955747
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955749
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966709
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FTH1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1354475
Menge 10 μg
Datenblatt Datenblatt
Reaktivität
Source Escherichia coli (E. coli)
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN1095588
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505081
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FTH1 Produkten

Mercer, Ohashi, Boeing, Jefferies, De Tito, Flynn, Tremel, Zhang, Wirth, Frith, Snijders, Williams, Tooze: "Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy." in: The EMBO journal, Vol. 40, Issue 14, pp. e105985, (2021) (PubMed).

Mai, Hamaï, Hienzsch, Cañeque, Müller, Wicinski, Cabaud, Leroy, David, Acevedo, Ryo, Ginestier, Birnbaum, Charafe-Jauffret, Codogno, Mehrpour, Rodriguez: "Salinomycin kills cancer stem cells by sequestering iron in lysosomes." in: Nature chemistry, Vol. 9, Issue 10, pp. 1025-1033, (2019) (PubMed).

Goodwin, Dowdle, DeJesus, Wang, Bergman, Kobylarz, Lindeman, Xavier, McAllister, Nyfeler, Hoffman, Murphy: "Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9." in: Cell reports, Vol. 20, Issue 10, pp. 2341-2356, (2018) (PubMed).

Inokura, Fujiwara, Saito, Iino, Hatta, Okitsu, Fukuhara, Onishi, Ishizawa, Shimoda, Harigae: "Impact of TET2 deficiency on iron metabolism in erythroblasts." in: Experimental hematology, Vol. 49, pp. 56-67.e5, (2017) (PubMed).

Kimura, Jia, Kumar, Choi, Gu, Mudd, Dupont, Jiang, Peters, Farzam, Jain, Lidke, Adams, Johansen, Deretic: "Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy." in: The EMBO journal, Vol. 36, Issue 1, pp. 42-60, (2017) (PubMed).

Yang, Gong, Yang, Zhang, Wang, Su, Wen, Zhang: "MR molecular imaging of tumours using ferritin heavy chain reporter gene expression mediated by the hTERT promoter." in: European radiology, Vol. 26, Issue 11, pp. 4089-4097, (2016) (PubMed).

Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).

Mancias, Pontano Vaites, Nissim, Biancur, Kim, Wang, Liu, Goessling, Kimmelman, Harper: "Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis." in: eLife, Vol. 4, (2016) (PubMed).

Banerjee, Sahoo, Anand, Bir, Chakrabarti: "The Oral Iron Chelator, Deferasirox, Reverses the Age-Dependent Alterations in Iron and Amyloid-β Homeostasis in Rat Brain: Implications in the Therapy of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 49, Issue 3, pp. 681-93, (2015) (PubMed).

Mumby, Ramakrishnan, Evans, Griffiths, Quinlan: "Methemoglobin-induced signaling and chemokine responses in human alveolar epithelial cells." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 1, pp. L88-100, (2014) (PubMed).

Synonyme und alternative Namen zu FTH1

ferritin heavy chain 1 (FTH1), ferritin, heavy polypeptide 1 L homeolog (fth1.L), ferritin, heavy polypeptide 1 S homeolog (fth1.S), ferritin heavy polypeptide 1 (Fth1), ferritin heavy chain 1 (Fth1), ferritin, heavy polypeptide 1a (fth1a), ferritin (EAMY_RS19690), ferritin, heavy polypeptide 1 (fth1), tudor domain containing 9 (TDRD9), ferritin, heavy polypeptide 1 (FTH1), ferritin, heavy polypeptide 1 a (fth1a), apoferritin, fb06g09, ferritin, FHC, fhc, FTH, fth, Fth, fth1, fth1b, FTHL6, fthl6, ftn-2, HFt, hm:zeh1145, MFH, PIG15, pig15, PLIF, plif, wu:fb06g09, wu:fq18c10, zeh1145

Bezeichner auf Proteinebene für FTH1

  • apoferritin
  • cell proliferation-inducing gene 15 protein
  • ferritin H subunit
  • ferritin heavy chain
  • placenta immunoregulatory factor
  • proliferation-inducing protein 15
  • ferritin H chain
  • XL2-17
  • ferritin H subunit A
  • ferritin heavy chain 2
  • ferritin heavy chain A
  • ferritin H subunit B
  • ferritin heavy chain 1
  • ferritin heavy chain B
  • ferritin, heavy polypeptide 1 b
  • ferritin heavy polypeptide 1
  • ferritin heavy-chain
  • H-ferritin
  • Ferritin subunit H
  • ferritin, heavy polypeptide 1
  • tudor domain containing 9
  • Ferritin H subunit
  • ferritin heavy chain 1 a
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