FLIP Produkte
(CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
Kategorien
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011].
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Ausgewählte FLIP Kategorien
FLIP Antikörper
High quality antibodies with extensive validation data.
FLIP ELISA Kits
Reliable ELISA kits for a wide range of species.
FLIP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FLIP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN1724850
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (7)
Kat. Nr.
ABIN563829
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7146901
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene FLIP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965446
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954407
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6213279
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FLIP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349226
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349225
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3091523
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FLIP Produkten
: "Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4." in: Cell reports, Vol. 21, Issue 12, pp. 3427-3444, (2018) (PubMed).: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
: "Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening." in: Breast cancer research : BCR, Vol. 16, Issue 2, pp. R41, (2014) (PubMed).
: "RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis." in: Nature, Vol. 513, Issue 7516, pp. 90-4, (2014) (PubMed).
: "Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 10, pp. 1154-62, (2013) (PubMed).
: "Release of an ~55kDa fragment containing the actin-binding domain of ?-spectrin by caspase-8 during FND-induced apoptosis depends on the presence of protein 4.1." in: Archives of biochemistry and biophysics, Vol. 535, Issue 2, pp. 205-13, (2013) (PubMed).
: "Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts." in: Pediatric blood & cancer, Vol. 60, Issue 4, pp. 575-9, (2013) (PubMed).
: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." in: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).
: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." in: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).
: "CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation." in: Journal of cellular biochemistry, Vol. 113, Issue 12, pp. 3692-700, (2012) (PubMed).
Synonyme und alternative Namen zu FLIP
CASP8 and FADD-like apoptosis regulator a (cflara), CASP8 and FADD like apoptosis regulator (CFLAR), CASP8 and FADD like apoptosis regulator (cflar), CASP8 and FADD like apoptosis regulator S homeolog (cflar.S), CASP8 and FADD-like apoptosis regulator (Cflar), 2310024N18Rik, A430105C05Rik, c-FLIP, c-Flip, c-FLIPL, c-FLIPR, c-FLIPS, CASH, Cash, CASP8AP1, Casper, cflar, CFLAR, CLARP, Clarp1, ENSMUSG00000072980, FLAME, FLAME-1, FLAME1, FLIP, Flip, Gm9845, I-FLICE, MRITBezeichner auf Proteinebene für FLIP
- FLIP
- CASP8 and FADD-like apoptosis regulator
- flice/caspase-i inhibitory protein
- cellular FLICE-like inhibitory protein
- CASP8 and FADD-like apoptosis regulator-like
- FADD-like anti-apoptotic molecule
- FADD-like antiapoptotic molecule 1
- MACH-related inducer of toxicity
- caspase homolog
- caspase-eight-related protein
- caspase-like apoptosis regulatory protein
- caspase-related inducer of apoptosis
- inhibitor of FLICE
- usurpin beta
- usurpin
- FLICE-like inhibitory protein
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